Succinylcholine chloride dihydrate (ab145759)

Overview

  • Product name
    Succinylcholine chloride dihydrate
  • Description
    Nicotinic AChR agonist, also acts as a depolarizing neuromuscular blocker.
  • Alternative names
    • Bis(trimethylammonioethyl) succinate chloride
    • Succinyldicholine dichloride
    • Suxamethonium chloride dihydrate
  • Biological description

    Cholinergic antagonist which induces a long-lasting depolarization of the acetylcholine neuron membrane; neuromuscular blocking agent.

Properties

  • Chemical name
    2,2-[(1,4-Dioxo-1,4-butanediyl)bis(oxy)]bis(N,N,N-trimethylethanaminium) chloride dihydrate
  • Molecular weight
    397.34
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C14H30Cl2N2O4.2H2O
  • CAS Number
    6101-15-1
  • Storage instructions
    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in DMSO to 2 mM and in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:
  • Limapichat W  et al. Chemical scale studies of the Phe-Pro conserved motif in the cys loop of Cys loop receptors. J Biol Chem 285:8976-84 (2010). Read more (PubMed: 20068044) »
  • Martyn JA & Richtsfeld M Succinylcholine-induced hyperkalemia in acquired pathologic states: etiologic factors and molecular mechanisms. Anesthesiology 104:158-69 (2006). Read more (PubMed: 16394702) »
  • Delvaux H  et al. Relative efficiency of succinylcholine, xylazine, and carfentanil/xylazine mixtures to immobilize free-ranging moose. J Wildl Dis 35:38-48 (1999). Read more (PubMed: 10073344) »
  • Abernethy MH  et al. A new succinylcholine-based assay of plasma cholinesterase. Clin Chem 30:192-5 (1984). Read more (PubMed: 6362911) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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