Overview

  • Product name
    Sulfobetaine 12
  • Description
    Zwitterionic detergent which retains its zwitterionic character over a broad pH range.
  • Alternative names
    • N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate
    • SB-12
    • SB3-12
    • Zwittergent 3-12
  • Biological description

    Synthetic zwitterionic detergent, which unlike other amphoteric surfactants, retains its zwitterionic character over a broad pH range. This property is attributed to the presence of both a strongly basic quaternary ammonium ion and an acidic sulfonate ion of equal strength. This ionic balance presumably prevents irreversible binding to either anionic or cationic compounds.

Properties

  • Molecular weight
    335.60
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C17H37NO3S
  • CAS Number
    14933-08-5
  • Storage instructions
    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in water
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:
  • Raper SE  et al. Identification and partial characterization of a somatostatin-14 binding protein on rat liver plasma membranes. Hepatology 16:433-9 (1992). Read more (PubMed: 1353473) »
  • Nollstadt KH  et al. Potential of the sulfobetaine detergent Zwittergent 3-12 as a desorbing agent in biospecific and bioselective affinity chromatography. J Chromatogr 497:87-100 (1989). Read more (PubMed: 2625482) »
  • Byers S  et al. The effect of zwitterionic detergents on the extraction and functional properties of cartilage proteoglycans. J Biol Chem 262:9166-74 (1987). Read more (PubMed: 3597409) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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