Overview

  • Product nameAnti-SULT2B1 antibody
    See all SULT2B1 primary antibodies
  • Description
    Mouse monoclonal to SULT2B1
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: MDGPAEPQIP GLWDTYEDDI SEISQKLPGE YFRYKGVPFP VGLYSLESIS, corresponding to amino acids 1-90 of human SULT2B1 protein (NP_814444) with a proprietary tag.

  • Positive control
    • MCF-7 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab88085 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 41 kDa.
ELISA Use at an assay dependent dilution.

Target

  • FunctionCatalyzes the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol.
  • Tissue specificityExpressed highly in placenta, prostate and trachea and lower expression in the small intestine and lung.
  • Sequence similaritiesBelongs to the sulfotransferase 1 family.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • Alcohol sulfotransferase antibody
    • EC 2.8.2.2 antibody
    • HSST2 antibody
    • Hydroxysteroid sulfotransferase 2 antibody
    • ST2B1 antibody
    • ST2B1_HUMAN antibody
    • Sulfotransferase 2B1 antibody
    • Sulfotransferase family cytosolic 2B member 1 antibody
    • SULT2B1 antibody
    • SULT2B1a antibody
    • SULT2B1b antibody
    see all

Anti-SULT2B1 antibody images

  • Anti-SULT2B1 antibody (ab88085) at 5 µg/ml + the immunogen at 0.2 µg

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

    Predicted band size : 41 kDa
    Observed band size : 38 kDa (why is the actual band size different from the predicted?)
  • Anti-SULT2B1 antibody (ab88085) at 5 µg/ml + MCF-7 cell lysate at 50 µg

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 41 kDa
    Observed band size : 41 kDa

References for Anti-SULT2B1 antibody (ab88085)

This product has been referenced in:
  • Vickman RE  et al. Cholesterol Sulfonation Enzyme, SULT2B1b, Modulates AR and Cell Growth Properties in Prostate Cancer. Mol Cancer Res 14:776-86 (2016). Read more (PubMed: 27341831) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab88085.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"