Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab87036 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/500.
WB 1/1000. Predicted molecular weight: 80 kDa.

Target

  • RelevanceSUN proteins form part of the LINC complex - a protein bridge that spans the nuclear envelope linking the nucleoskeleten to the actin cytoskeleten. They are located on the inner nuclear membrane side of the complex. The LINC complex is thought to function in controlling nuclear position, contributing to mechanical resistance and the overall architecture of the cell. SUN2 can exist in a heterodimer with SUN1. Both can interact with lamins and nesprins in the nuclear envelope.
  • Cellular localizationNuclear membrane, endosome membrane, mitotic spindle organization.
  • Database links
  • Alternative names
    • FRIGG antibody
    • KIAA0668 antibody
    • nuclear envelope protein antibody
    • Protein unc-84 homolog B antibody
    • Rab5 interacting protein antibody
    • RAB5IP antibody
    • Sad1 and UNC84 domain containing 2 antibody
    • Sad1 unc-84 domain protein 2 antibody
    • Sad1 unc84 domain protein antibody
    • Sad1/unc-84 protein-like 2 antibody
    • Sad1/unc84 protein-like antibody
    • SUN domain-containing protein 2 antibody
    • UNC 84B antibody
    • unc84 homolog B (C. elegans) antibody
    • unc84 homolog B antibody
    • unc84, C. elegans, homolog of, B antibody
    • UNC84B antibody
    see all

Anti-SUN2 antibody images

  • Immunofluorescence showing ab87036  on NIH 3T3 cells fixed with PFA

References for Anti-SUN2 antibody (ab87036)

This product has been referenced in:
  • Gutiérrez-Fernández A  et al. Loss of MT1-MMP causes cell senescence and nuclear defects which can be reversed by retinoic acid. EMBO J 34:1875-88 (2015). Read more (PubMed: 25991604) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"