Overview

  • Product name
  • Description
    Rabbit polyclonal to Surf1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Horse, Guinea pig, Cat
  • Immunogen

    Synthetic peptide, corresponding to a region within N terminal amino acids 10-59 (GLRAAGLGRA PASAAWRSVL RVSPRPGVAW RPSRCGSSAA EASATKAEDD) of Human Surf1 (NP_003163).

  • Positive control
    • HepG2 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab117945 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 33 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Probably involved in the biogenesis of the COX complex.
  • Involvement in disease
    Defects in SURF1 are a cause of Leigh syndrome (LS) [MIM:256000]. LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions that is commonly associated with systemic cytochrome c oxidase (COX) deficiency.
  • Sequence similarities
    Belongs to the SURF1 family.
  • Cellular localization
    Mitochondrion inner membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • OTTHUMP00000022473 antibody
    • OTTHUMP00000022474 antibody
    • SURF 1 antibody
    • SURF-1 antibody
    • Surf1 antibody
    • SURF1_HUMAN antibody
    • Surfeit 1 antibody
    • Surfeit locus protein 1 antibody
    see all

Images

  • Anti-Surf1 antibody (ab117945) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Predicted band size : 33 kDa

References

ab117945 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab117945.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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