Anti-Surfactant protein D antibody [SPDE] (ab15687)

Overview

  • Product nameAnti-Surfactant protein D antibody [SPDE]
    See all Surfactant protein D primary antibodies
  • Description
    Mouse monoclonal [SPDE] to Surfactant protein D
  • SpecificityRat: SPDE recognizes a conformational epitope of SP-D Other Species: Positive on human tissues.
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    Purified rat surfactant protein D from bronchoalveolar lavage.

Properties

Applications

Our Abpromise guarantee covers the use of ab15687 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.
WB Use at an assay dependent concentration. Predicted molecular weight: 43 kDa.

Target

  • FunctionContributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
  • Sequence similaritiesBelongs to the SFTPD family.
    Contains 1 C-type lectin domain.
    Contains 1 collagen-like domain.
  • Post-translational
    modifications
    The N-terminus is blocked.
    Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates.
  • Cellular localizationSecreted > extracellular space > extracellular matrix. Secreted > extracellular space > surface film.
  • Information by UniProt
  • Database links
  • Alternative names
    • COLEC 7 antibody
    • COLEC7 antibody
    • Collectin-7 antibody
    • Collectin7 antibody
    • Lung surfactant protein D antibody
    • PSP D antibody
    • PSP-D antibody
    • PSP-D Surfactant protein D antibody
    • PSPD antibody
    • Pulmonary surfactant apoprotein antibody
    • Pulmonary surfactant associated protein D antibody
    • Pulmonary surfactant associated protein PSP-D antibody
    • Pulmonary surfactant-associated protein D antibody
    • SFTP 4 antibody
    • SFTP4 antibody
    • SFTPD antibody
    • SFTPD_HUMAN antibody
    • SP D antibody
    • SP-D antibody
    • Surfactant associated protein pulmonary 4 antibody
    • Surfactant pulmonary associated protein D antibody
    see all

References for Anti-Surfactant protein D antibody [SPDE] (ab15687)

This product has been referenced in:
  • Madsen C  et al. Small molecule inhibitors of Ago2 decrease Venezuelan equine encephalitis virus replication. Antiviral Res 112:26-37 (2014). Read more (PubMed: 25448087) »

See 1 Publication for this product

Product Wall

Thank you for your phone call earlier today. I checked about the Surfactant protein D antibody you were looking for. We currently have several mouse monoclonal antibodies that may be suitable: ab17781, ab15696, ab15695 and ab15687 for example. I hope t...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"