The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesELISA: Use at a concentration of 2 µg/ml.
IHC-P: 1/20 (human) - 1/400 (rat).
WB: Use at an assay dependent dilution. Predicted molecular weight: 43 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionContributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
Sequence similaritiesBelongs to the SFTPD family. Contains 1 C-type lectin domain. Contains 1 collagen-like domain.
Post-translational modificationsThe N-terminus is blocked. Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates.
Cellular localizationSecreted > extracellular space > extracellular matrix. Secreted > extracellular space > surface film.
Pulmonary surfactant associated protein D antibody
Pulmonary surfactant associated protein PSP-D antibody
Pulmonary surfactant-associated protein D antibody
SFTP 4 antibody
SP D antibody
Surfactant associated protein pulmonary 4 antibody
Surfactant pulmonary associated protein D antibody
References for Anti-Surfactant protein D antibody [VI F11] (ab15688)
This product has been referenced in:
Yadav AK et al. Differential expression of collectins in human placenta and role in inflammation during spontaneous labor. PLoS One9:e108815 (2014).
Read more (PubMed: 25303045) »
Kasper M et al. Monoclonal antibodies to surfactant protein D: evaluation of immunoreactivity in normal rat lung and in a radiation-induced fibrosis model. Exp Lung Res21:577-88 (1995).
Read more (PubMed: 7588444) »