Anti-SUV420h1 antibody (ab104875)
Key features and details
- Rabbit polyclonal to SUV420h1
- Suitable for: ELISA, ICC, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-SUV420h1 antibody -
Description
Rabbit polyclonal to SUV420h1 -
Host species
Rabbit -
Tested applications
Suitable for: ELISA, ICC, WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Synthetic peptides derived from internal domains of Human SUV420h1.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
Constituent: Whole serum -
Concentration information loading...
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Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab104875 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use at an assay dependent concentration.
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ICC |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration.
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Notes |
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ELISA
Use at an assay dependent concentration. |
ICC
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
Target
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Function
Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity). Plays a role in myogenesis by regulating the expression of target genes, such as EID3. -
Sequence similarities
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.
Contains 1 SET domain. -
Cellular localization
Nucleus. Chromosome. Associated with pericentric heterochromatin. CBX1 and CBX5 are required for the localization to pericentric heterochromatin (By similarity). - Information by UniProt
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Database links
- Entrez Gene: 51111 Human
- Entrez Gene: 225888 Mouse
- Omim: 610881 Human
- SwissProt: Q4FZB7 Human
- SwissProt: Q3U8K7 Mouse
- Unigene: 632120 Human
- Unigene: 278578 Mouse
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Alternative names
- CGI 85 antibody
- CGI85 antibody
- Histone-lysine N-methyltransferase KMT5B antibody
see all
Protocols
Datasheets and documents
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Datasheet download
References (0)
ab104875 has not yet been referenced specifically in any publications.