Overview

  • Product nameAnti-Su(var)3-9 antibody
  • Description
    Rabbit polyclonal to Su(var)3-9
  • Specificityab4811 will recognise KMT1 / Clr4 / Su(var)3-9 but not eIF2-gamma due to immunogen selection.
  • Tested applicationsSuitable for: ICC/IFmore details
  • Species reactivity

    Predicted to work with: Drosophila melanogaster
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 150 - 250 of Fruit fly (Drosophila melanogaster) KMT1/ Clr4/ Su(var)3-9.

    (Peptide available as ab87896.)

Properties

Applications

Our Abpromise guarantee covers the use of ab4811 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/100.

Target

  • RelevanceHistone-lysine N-methyltransferase, H3 lysine-9 specific. Major histone methyltransferase. Methylates Lys-9 of histone H3. H3 Lys-9 methylation represents a specific tag for epigenetic transcriptional repression by recruiting Su(var)205/HP1 to methylated histones. Seems to be involved in heterochromatic gene silencing including the modification of position-effect-variegation. There are three isoforms, isoform A and isoform B share the first 80 amino acid residues. Experimental confirmation may be lacking for some isoforms.
  • Cellular localizationNuclear
  • Database links
    • Alternative names
      • H3-K9-HMTase antibody
      • Histone H3-K9 methyltransferase antibody
      • Su(var)3-9 antibody
      • Suppressor of variegation protein 3-9 antibody
      • suv39 antibody
      see all

    References for Anti-Su(var)3-9 antibody (ab4811)

    ab4811 has not yet been referenced specifically in any publications.

    Product Wall

    Application Immunocytochemistry/ Immunofluorescence
    Sample Stylonychia lemnae Cell (single cell organism)
    Specification single cell organism
    Fixative Paraformaldehyde
    Permeabilization Yes - 0.5%TritonX100/PBS, brief 0.1N HCl treatment, brief pepsin treatment
    Blocking step BSA as blocking agent for 30 minute(s) · Concentration: 4% · Temperature: 20°C
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    Submitted Jul 20 2007

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"