Anti-Swine H1N1 Nonstructural Protein 1 antibody (ab91647)

Overview

  • Product nameAnti-Swine H1N1 Nonstructural Protein 1 antibody
  • Description
    Rabbit polyclonal to Swine H1N1 Nonstructural Protein 1
  • Specificityab91647 is specific for the Swine H1N1 Nonstructural Protein 1 and will not recognize the corresponding NS1 sequence from the seasonal H1N1 influenza (A/South Australia/51/2005 (H1N1)).
  • Tested applicationsSuitable for: ELISAmore details
  • Species reactivity
    Influenza A virus
  • Immunogen

    A synthetic peptide containing the sequence specific to the novel Swine H1N1 Nonstructural Protein 1 (Genbank accession no. ACP41110).

Properties

Applications

Our Abpromise guarantee covers the use of ab91647 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
  • Application notesELISA: Use at a concentration of 1 µg/ml.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceInfluenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus (S-OIV) was identified in specimens obtained from patients in Mexico and the United States. One of the less studied proteins encoded by, but not incorporated in, the influenza virus is the Swine H1N1 Nonstructural Protein 1. It counters cellular antiviral activities and acts as a virulence factor. It can bind to double-stranded RNA and sequester it from 2’-5’ OAS, preventing the activation of the RNAse L, which normally acts to degrade RNA and prevent virus replication. It also binds to and inhibits the anti-viral protein kinase PKR.
    • Alternative names
      • S-OIV NS1 antibody
      • Swine origin Influenza A (H1N1) Nonstructural Protein 1 antibody

    Anti-Swine H1N1 Nonstructural Protein 1 antibody images

    • ab91647, at a concentration of 1 µg/ml, detects swine-origin H1N1 Nonstructural Protein 1 peptide. It does not crossreact with peptide corresponding to the seasonal H1N1 Nonstructural Protein 1. The blocking and corresponding peptides were used at 60, 10, 2 and 0 ng/ml.

    References for Anti-Swine H1N1 Nonstructural Protein 1 antibody (ab91647)

    ab91647 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"