Overview

  • Product nameAnti-Synapsin I antibody
    See all Synapsin I primary antibodies
  • Description
    Mouse monoclonal to Synapsin I
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: EIFGGLDICA VEALHGKDGR DHIIEVVGSS MPLIGDHQDE DKQLIVELVV NKMAQALPRQ RQRDASPGRG SHGQTPSPGA LPLGRQTSQ, corresponding to amino acids 362-451 of Human Synapsin I

Properties

Applications

Our Abpromise guarantee covers the use of ab57467 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionNeuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.
    • Involvement in diseaseDefects in SYN1 are a cause of epilepsy X-linked with variable learning disabilities and behavior disorders [MIM:300491]. XELBD is characterized by variable combinations of epilepsy, learning difficulties, macrocephaly, and aggressive behavior.
    • Sequence similaritiesBelongs to the synapsin family.
    • Post-translational
      modifications
      Substrate of at least four different protein kinases. It is probable that phosphorylation plays a role in the regulation of synapsin-1 in the nerve terminal. Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localizationCell junction > synapse. Golgi apparatus.
    • Information by UniProt
    • Database links
    • Alternative names
      • Brain protein 4.1 antibody
      • SYN 1 antibody
      • SYN 1a antibody
      • SYN 1b antibody
      • SYN I antibody
      • SYN1 antibody
      • SYN1_HUMAN antibody
      • SYN1a antibody
      • SYN1b antibody
      • Synapsin 1 antibody
      • Synapsin I antibody
      • Synapsin-1 antibody
      • Synapsin1 antibody
      • SynapsinI antibody
      • SYNI antibody
      see all

    Anti-Synapsin I antibody images



    • Predicted band size : 70 kDa
      Synapsin I antibody (ab57467) at 1ug/lane + MCF-7 cell lysate at 25ug/lane.

    References for Anti-Synapsin I antibody (ab57467)

    ab57467 has not yet been referenced specifically in any publications.

    Product Wall

    Application Immunocytochemistry/ Immunofluorescence
    Sample Human Cell (Poor)
    Permeabilization Yes - 0.2% Triton-X-100
    Specification Poor
    Blocking step BSA as blocking agent for 30 minute(s) · Concentration: 10µg/mL · Temperature: 25°C
    Fixative Formaldehyde
    Username

    Dr. Amy Zhu

    Verified customer

    Submitted May 20 2016

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"