Anti-Synapsin I (phospho S603) antibody (ab13879)

Overview

  • Product nameAnti-Synapsin I (phospho S603) antibody
    See all Synapsin I primary antibodies
  • Description
    Rabbit polyclonal to Synapsin I (phospho S603)
  • SpecificityThe antibody is specific for Synapsin I phosphorylated at Ser603.
  • Tested applicationsSuitable for: Dot blot, WBmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    This antibody was developed against synthetic phosphopeptide corresponding to amino acids residues surrounding the phospho-Ser603 of rat Synapsin I.

  • General notesAliquots may be taken without freeze/thawing due to the presence of 50% glycerol.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 100µg/ml BSA, 150mM Sodium Chloride, 10mM HEPES. pH 7.5
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesThe antibody was purified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab13879 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Dot blot 1/1000.
WB 1/1000. Predicted molecular weight: 84.6 kDa.

Target

  • FunctionNeuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.
  • Involvement in diseaseDefects in SYN1 are a cause of epilepsy X-linked with variable learning disabilities and behavior disorders [MIM:300491]. XELBD is characterized by variable combinations of epilepsy, learning difficulties, macrocephaly, and aggressive behavior.
  • Sequence similaritiesBelongs to the synapsin family.
  • Post-translational
    modifications
    Substrate of at least four different protein kinases. It is probable that phosphorylation plays a role in the regulation of synapsin-1 in the nerve terminal. Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationCell junction > synapse. Golgi apparatus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Brain protein 4.1 antibody
    • SYN 1 antibody
    • SYN 1a antibody
    • SYN 1b antibody
    • SYN I antibody
    • SYN1 antibody
    • SYN1_HUMAN antibody
    • SYN1a antibody
    • SYN1b antibody
    • Synapsin 1 antibody
    • Synapsin I antibody
    • Synapsin-1 antibody
    • Synapsin1 antibody
    • SynapsinI antibody
    • SYNI antibody
    see all

Anti-Synapsin I (phospho S603) antibody images



  • Predicted band size : 84.6 kDa


    Right lane-ab13879 at 1/1000 dilution detecting synapsin I by Western blot. Left lane-Peptide block.

References for Anti-Synapsin I (phospho S603) antibody (ab13879)

ab13879 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. I can confirm that the immunogen for this product is phospho-Ser603 of rat Synapsin I. I sincerely apologize that we had a typing error on the datasheet and rest assured that it has now been corrected. Thank you agai...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"