• Product name
    Anti-Synapsin II antibody [EPR3277]
    See all Synapsin II primary antibodies
  • Description
    Rabbit monoclonal [EPR3277] to Synapsin II
  • Tested applications
    Suitable for: WB, IHC-Pmore details
    Unsuitable for: Flow Cyt,ICC/IF or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (Human)

  • Positive control
    • WB: fetal brain cell lysate; IHC-P: human brain tissue;
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.


Associated products


Our Abpromise guarantee covers the use of ab76494 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/5000 - 1/20000. Predicted molecular weight: 63 kDa.Can be blocked with Synapsin II peptide (ab177842).
IHC-P 1/100 - 1/250.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF or IP.
  • Target

    • Relevance
      Synapsin II is a member of the synapsin gene family. Synapsins are neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family is a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal.
    • Cellular localization
      Cell junction, synapse.
    • Database links
    • Alternative names
      • SYN 2 antibody
      • SYN II antibody
      • SYN IIa antibody
      • SYN IIb antibody
      • SYN2 antibody
      • Synapsin 2 antibody
      • Synapsin II isoform IIa antibody
      • Synapsin II isoform IIb antibody
      • Synapsin2 antibody
      • SynapsinII antibody
      • SYNII antibody
      • SYNIIa antibody
      • SYNIIb antibody
      see all

    Anti-Synapsin II antibody [EPR3277] images

    • Anti-Synapsin II antibody [EPR3277] (ab76494) at 1/20000 dilution + fetal brain cell lysate at 10 µg

      HRP labelled goat anti-rabbit at 1/1000 dilution

      Predicted band size : 63 kDa
      Observed band size : 75 kDa (why is the actual band size different from the predicted?)
    • Immunohistochemical analysis of paraffin-embedded human brain tissue using 1/100 ab76494

    References for Anti-Synapsin II antibody [EPR3277] (ab76494)

    This product has been referenced in:
    • Wei H  et al. Diffuse and specific tectopulvinar terminals in the tree shrew: synapses, synapsins, and synaptic potentials. PLoS One 6:e23781 (2011). IHC (PFA fixed) . Read more (PubMed: 21858222) »
    • Agostini M  et al. Neuronal differentiation by TAp73 is mediated by microRNA-34a regulation of synaptic protein targets. Proc Natl Acad Sci U S A 108:21093-8 (2011). WB . Read more (PubMed: 22160687) »

    See all 2 Publications for this product

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