Overview

  • Product nameAnti-Synaptojanin antibody
    See all Synaptojanin primary antibodies
  • Description
    Rabbit polyclonal to Synaptojanin
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within: GVARREMEAP KSPGTTRKDN IGRSQPSPQA GLAGPGPAGY STARPTIPPR, internal sequence amino acids 1152-1201 of Human Synaptojanin (NP_003886)

  • Positive control
    • Human fetal stomach lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab94912 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 173 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionInositol 5-phosphatase which has a role in clathrin-mediated endocytosis.
  • Tissue specificityConcentrated at clathrin-coated endocytic intermediates in nerve terminals. Isoform 1 is more enriched than isoform 2 in developing brain as well as non-neuronal cells. Isoform 2 is very abundant in nerve terminals.
  • Sequence similaritiesBelongs to the synaptojanin family.
    In the central section; belongs to the inositol-1,4,5-trisphosphate 5-phosphatase family.
    Contains 1 RRM (RNA recognition motif) domain.
    Contains 1 SAC domain.
  • DomainBinds to EPS15 (a clathrin coat-associated protein) via a C-terminal domain containing three Asn-Pro-Phe (NPF) repeats.
    The C-terminal proline-rich region mediates binding to a variety of SH3 domain-containing proteins including AMPH, SH3GL1, SH3GL2, SH3GL3 and GRB2.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • 4 antibody
    • 5-trisphosphate 5-phosphatase 1 antibody
    • Inositol 5' phosphatase (synaptojanin 1) antibody
    • Inositol 5' phosphatase antibody
    • INPP 5G antibody
    • INPP5G antibody
    • KIAA0910 antibody
    • PARK20 antibody
    • Polyphosphoinositide phosphatase antibody
    • Synaptic inositol 1 4 5 trisphosphate 5 phosphatase 1 antibody
    • Synaptic inositol 145 trisphosphate 5 phosphatase 1 antibody
    • Synaptic inositol-1 antibody
    • Synaptojanin 1 antibody
    • Synaptojanin 1 polyphosphoinositide phosphatase antibody
    • Synaptojanin-1 antibody
    • Synaptojanin1 antibody
    • Synj 1 antibody
    • Synj1 antibody
    • SYNJ1_HUMAN antibody
    see all

Anti-Synaptojanin antibody images

  • Anti-Synaptojanin antibody (ab94912) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal stomach lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 173 kDa

References for Anti-Synaptojanin antibody (ab94912)

ab94912 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab94912.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"