Overview

  • Product nameAnti-Synaptopodin antibody
    See all Synaptopodin primary antibodies
  • Description
    Rabbit polyclonal to Synaptopodin
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide from the C terminal region of Human Synaptopodin, conjugated to KLH.

  • Positive control
    • Human perineural or perivascular process.

Properties

Applications

Our Abpromise guarantee covers the use of ab117702 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 99 kDa.
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 5 µg/ml.

Target

  • FunctionActin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity.
  • Tissue specificityExpressed in cerebral cortex.
  • Sequence similaritiesBelongs to the synaptopodin family.
  • Post-translational
    modifications
    O-glycosylated.
    Isoform 2 is phosphorylated on Ser-826, Thr-836, Ser-840 and Ser-871.
  • Cellular localizationCytoplasm > cytoskeleton. Cell junction > tight junction. Perikaryon. Cell projection > dendritic spine. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse. Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Asssociated with dendritic spines of a subset of synapses.
  • Information by UniProt
  • Database links
  • Alternative names
    • KIAA1029 antibody
    • Synaptopodin antibody
    • SYNPO antibody
    • SYNPO_HUMAN antibody

Anti-Synaptopodin antibody images

  • Human Perineural Processes, Formalin-Fixed, Paraffin-Embedded tissue, stained with ab117702 at 5µg/ml.
  • Human Perivascular Processes, Formalin-Fixed, Paraffin-Embedded tissue, stained with ab117702 at 5µg/ml.

References for Anti-Synaptopodin antibody (ab117702)

ab117702 has not yet been referenced specifically in any publications.

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