Anti-Synaptotagmin antibody (ab51172)


  • Product nameAnti-Synaptotagmin antibody
    See all Synaptotagmin primary antibodies
  • Description
    Rabbit polyclonal to Synaptotagmin
  • SpecificityThis antibody reacts with endogenous levels of total Synaptotagmin protein.
  • Tested applicationsELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    A synthesized non-phosphopeptide derived from human Synaptotagmin around the phosphorylation site of threonine 202.

  • Positive control
    • Human breast carcinoma tissue



Our Abpromise guarantee covers the use of ab51172 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/10000.
IHC-P Use at an assay dependent dilution.


  • RelevanceThe synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin participates in triggering neurotransmitter release at the synapse. The first C2 domain mediates Ca(2+)-dependent phospholipid binding. The second C2 domain mediates interaction with Stonin 2. Synaptotagmin may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.
  • Cellular localizationCytoplasmic
  • Database links
  • Alternative names
    • DKFZp781D2042 antibody
    • P65 antibody
    • SVP65 antibody
    • Synaptotagmin I antibody
    • Synaptotagmin II antibody
    • Synaptotagmin IV antibody
    • Synaptotagmin V antibody
    • SYT 1 antibody
    • SYT antibody
    • SYT1 antibody
    • SYT2 antibody
    • SYT3 antibody
    • SYT4 antibody
    • SYT5 antibody
    • SytI antibody
    see all

Anti-Synaptotagmin antibody images

  • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ab51172 at a 1:50 dilution. Left image un-treated; Right image treated with peptide.

References for Anti-Synaptotagmin antibody (ab51172)

ab51172 has not yet been referenced specifically in any publications.

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Thank you for providing the sequence and for your patience.

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