Anti-Synaptotagmin antibody [ASV48] (ab90461)

Overview

  • Product nameAnti-Synaptotagmin antibody [ASV48]
    See all Synaptotagmin primary antibodies
  • Description
    Mouse monoclonal [ASV48] to Synaptotagmin
  • Specificityab90461 detects an ~65 kDa protein, corresponding to the apparent molecular mass of Synaptotagmin on SDS-PAGE immunoblots.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Fish, Monkey, Shark
  • Immunogen

    Rat brain synaptic junction protein complexes

  • Positive control
    • Mouse or rat brain cytoplasmic lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab90461 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 0.1 µg/ml. Sufficient for detection of Synaptotagmin in 20µg of rat brain tissue extract by colorimetric immunoblot analysis.
    Predicted molecular weight: 47 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMay have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
    • Sequence similaritiesBelongs to the synaptotagmin family.
      Contains 2 C2 domains.
    • DomainThe first C2 domain mediates Ca(2+)-dependent phospholipid binding.
      The second C2 domain mediates interaction with Stonin 2.
    • Cellular localizationCytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane. Synaptic vesicles and chromaffin granules.
    • Information by UniProt
    • Database links
    • Alternative names
      • HsT1192 antibody
      • MYSPC antibody
      • P65 antibody
      • SVP65 antibody
      • synaptotagmin 4 antibody
      • Synaptotagmin I antibody
      • Synaptotagmin II antibody
      • Synaptotagmin IV antibody
      • Synaptotagmin V antibody
      • Synaptotagmin-2 antibody
      • synaptotagmin-3 antibody
      • SYT antibody
      • SYT1 antibody
      • Syt2 antibody
      • SYT2_HUMAN antibody
      • SYT3 antibody
      • SYT4 antibody
      • SYT5 antibody
      • SytII antibody
      • SytIII antibody
      • sytIV antibody
      see all

    References for Anti-Synaptotagmin antibody [ASV48] (ab90461)

    ab90461 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for providing the sequence and for your patience.

    After aligning the sequences, I am afraid it is not very likely that any of the Anti-Synaptotagmin antibodies available will recognise the Arabidopsis protein, as the homologies are ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"