Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Products:Neuroscience >> Cell Adhesion Proteins >> Membrane Proteins
Overview
Product name
Anti-Syndecan antibody [B-A38] (Phycoerythrin)
See all Syndecan products (13) ...
Description
Mouse monoclonal [B-A38] to Syndecan (Phycoerythrin)
Conjugation
Phycoerythrin
Conjugation notes
Purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions.
Tested applications
Flow Cytmore details
Cross reactivity
Reacts with
Human
Immunogen
U266 human peripheral blood myeloma cell line
Positive control
Human blood cells.
Properties
Form
Liquid
Storage instructions
Store at +4°C in the dark. Do not freeze.
Storage buffer
Preservative: 15mM Sodium Azide
Constituents: 0.2% (w/v) high-grade protease free BSA, PBS
Concentration
Concentration information loading...
Purity
Size exclusion
Purification notes
The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
Clonality
Monoclonal
Clone number
B-A38
Isotype
IgG1
Research areas
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> B Lymphocytic Lineage
Cancer >> Invasion/microenvironment >> ECM >> Extracellular matrix >> Other
Signal Transduction >> Cytoskeleton / ECM >> HSPGs
Neuroscience >> Neurology process >> Neurogenesis
Neuroscience >> Cell Type Marker >> Neuron marker >> Synapse marker
Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Proteins >> Glucosaminoglycans
Neuroscience >> Cell Adhesion Proteins >> ECM Proteins
Neuroscience >> Cell Adhesion Proteins >> Membrane Proteins
Applications
Show applications key
Our Abpromise guarantee covers the use of ab77224 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Flow Cyt
Application notes
Flow Cyt: Use 20µl for 106 cells or 100µl of whole blood.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.
Sequence similarities
Belongs to the syndecan proteoglycan family.
Cellular localization
Membrane.
Target information above from: UniProt accessionP18827
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- CD 138 antibody
- CD138 antibody
- CD138 antigen antibody
see all
Database links
- Entrez Gene: 6382 Human
- Omim: 186355 Human
- SwissProt: P18827 Human
- Unigene: 224607 Human
- Unigene: 665958 Human
References for Anti-Syndecan antibody [B-A38] (Phycoerythrin) (ab77224)
This product has been referenced in:
- Yang Yet al. The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy. Blood 110:2041-8 (2007).Read more (PubMed: 17536013) »
- Cheriyath Vet al. G1P3, an IFN-induced survival factor, antagonizes TRAIL-induced apoptosis in human myeloma cells. J Clin Invest 117:3107-17 (2007).Read more (PubMed: 17823654) »
See all 3 publications for this product
Publishing research using ab77224? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"