Overview

  • Product nameAnti-SYNRG antibody
    See all SYNRG primary antibodies
  • Description
    Rabbit polyclonal to SYNRG
  • Tested applicationsSuitable for: ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rhesus monkey
  • Immunogen

    antigen sequence, corresponding to amino acids 46-158 of Human SYNRG.

  • Positive control
    • Human cerebral cortex tissue.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferpH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab121761 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionMay play a role in endocytosis and/or membrane trafficking at the trans-Golgi network (TGN). May act by linking the adapter protein complex AP-1 to other proteins.
  • Sequence similaritiesContains 1 EH domain.
  • DomainThe DFXDF motifs mediate the interaction with gamma-appendage subunits AP1G1 and AP1G2.
  • Cellular localizationCytoplasm. Golgi apparatus > trans-Golgi network membrane. Associates with membranes via the adapter protein complex AP-1. Colocalizes with AP1G1.
  • Information by UniProt
  • Database links
  • Alternative names
    • AP1 subunit gamma-binding protein 1 antibody
    • AP1GBP1 antibody
    • Gamma-synergin antibody
    • Synergin gamma antibody
    • SYNG antibody
    • Synrg antibody
    • SYNRG_HUMAN antibody
    see all

Anti-SYNRG antibody images

  • Immunofluorescent staining of Human cell line U-2 OS shows positivity in nucleus but not nucleoli and cytoplasm. Recommended concentration of ab121761 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab121761 at 1/75 dilution staining SYNRG in Paraffin-embedded Human cerebral cortex tissue by Immunohistochemistry.

References for Anti-SYNRG antibody (ab121761)

ab121761 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"