Syntaxin 1A + Syntaxin 1B2 peptide (2-13) (ab45797)

Overview

  • Product nameSyntaxin 1A + Syntaxin 1B2 peptide (2-13)

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceKDRTQELRTAKD-C
    • Amino acids2 to 13

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45797 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Syntaxin 1A + Syntaxin 1B2 antibody (ab39986)

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • adipocyte C1Q and collagen domain containing
    • adiponectin
    • adipose most abundant gene transcript 1
    • HPC 1
    • p35 1
    • STX1
    • STX1A
    • STX1B1
    • STX1B2
    see all
  • RelevanceSyntaxins are potentially involved in the docking of synaptic vesicles at presynaptic active zones and may play a key role in neurotransmitter exocytosis. Three isoforms are produced by alternative splicing. Isoform 1 is expressed in embryonic spinal chord and ganglia and in adult cerebellum and cerebral cortex. Isoform 2 is expressed in heart, liver, fat, skeletal muscle, kidney and brain. Syntaxin 1A interacts with VAPA and SYBU and is a member of the SNARE core complex containing SNAP25 and VAMP2. In addition, it is found in complexes with SNAP25, SNAP23 and VAMP8. Haploinsufficiency of STX1A may result in particular cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome, a rare developmental disorder.
  • Cellular localizationCell membrane; single-pass type IV membrane protein; Isoform 2 is thought to be secreted

References for Syntaxin 1A + Syntaxin 1B2 peptide (2-13) (ab45797)

ab45797 has not yet been referenced specifically in any publications.

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