Overview

  • Product name
  • Description
    Rabbit polyclonal to Syntaxin 2
  • Tested applications
    Suitable for: WB, IP, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Sheep, Rabbit, Chicken, Hamster, Cow, Dog, Human, Pig, Xenopus laevis, Drosophila melanogaster, Monkey
  • Immunogen

    Synthetic peptide:

    MRDRLPDLTACRKSDDGDN

    corresponding to amino acids 1-19 of Rat Syntaxin 2, conjugated to KLH.

  • Positive control
    • Human brain, cerebellum tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    pH: 7.20
    Preservative: 0.09% Sodium azide
    Constituents: 50% Glycerol, 49% PBS
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab118829 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 33 kDa).
IP Use a concentration of 10 µg/ml.
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
  • Sequence similarities
    Belongs to the syntaxin family.
    Contains 1 t-SNARE coiled-coil homology domain.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Form
    Inhibition of syntaxin-2 and Vamp8 function by overexpression of nonmembrane-anchored mutants caused failure of cytokinesis leading to the formation of binucleated cells. There are 3 isoforms produced by alternative splicing.
  • Alternative names
    • EPIM antibody
    • Epimorphin antibody
    • EPM antibody
    • MGC51014 antibody
    • OTTHUMP00000238636 antibody
    • OTTHUMP00000238637 antibody
    • Stx2 antibody
    • STX2_HUMAN antibody
    • STX2A antibody
    • STX2B antibody
    • STX2C antibody
    • Syntaxin 2A antibody
    • Syntaxin 2B antibody
    • Syntaxin 2C antibody
    • Syntaxin-2 antibody
    see all

Images

  • ab118829, at 10 µg/ml, staining Syntaxin 2 in formalin fixed, paraffin embedded Human brain cerebellum tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References

ab118829 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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