The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
It is recommended vials be centrifuged prior to opening. Water can be used to prepare stock solutions of 20 µmol.L-1. Stock solutions with up to 30% DMSO/water can also be prepared.
Breast and kidney
C-X-C motif chemokine 14
C-X-C motif chemokine ligand 14
Chaemokine, CXC motif, ligand 14
Chemokine (C-X-C motif) ligand 14
CXC chemokine in breast and kidney
Kidney-expressed chemokine CXC
MIP 2 gamma
Small Inducible Cytokine B14
Small inducible cytokine subfamily B (Cys-X-Cys) member 14 (BRAK)
Small Inducible Cytokine subfamily B, member 14
Small-inducible cytokine B14
Tumor suppressing chemokine
Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactive for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays.
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highly expressed in normal tissue without inflammatory stimuli and infrequently expressed in cancer cell lines. Weakly expressed in monocyte-derived dendritic cells. Not detected in lung or unstimulated peripheral blood lymphocytes.
Belongs to the intercrine alpha (chemokine CxC) family.