Overview

  • Product name
  • Description
    Rabbit polyclonal to SYT11
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide derived from internal sequence of Human SYT11.

  • Positive control
    • Extracts from COLO205 cells

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer
    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 0.88% Sodium chloride, 50% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab110766 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 48 kDa.

Target

  • Function
    May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.
  • Sequence similarities
    Belongs to the synaptotagmin family.
    Contains 2 C2 domains.
  • Post-translational
    modifications
    Ubiquitinated and targeted to the proteasome complex for degradation.
  • Cellular localization
    Membrane. Cell junction > synapse. Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. In substantia nigra, observed in neuronal cell bodies and neurites. Found in the core of the Lewy bodies in the brain of sporadic Parkinson disease patients.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp781D015 antibody
    • KIAA0080 antibody
    • MGC10881 antibody
    • MGC17226 antibody
    • Synaptotagmin 11 antibody
    • Synaptotagmin 12 antibody
    • Synaptotagmin XI antibody
    • Synaptotagmin-11 antibody
    • Synaptotagmin11 antibody
    • Synaptotagmin12 antibody
    • SynaptotagminXI antibody
    • SYT 11 antibody
    • SYT 12 antibody
    • Syt XI antibody
    • Syt11 antibody
    • SYT11_HUMAN antibody
    • SYT12 antibody
    • SytXI antibody
    see all

Images

  • All lanes : Anti-SYT11 antibody (ab110766) at 1/500 dilution

    Lane 1 : Extracts from COLO205 cells
    Lane 2 : Extracts from COLO205 cells with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 48 kDa

References

ab110766 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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