Anti-T-bet / Tbx21 antibody [39D, 3-9D] (ab91103)

Overview

  • Product nameAnti-T-bet / Tbx21 antibody [39D, 3-9D]
    See all T-bet / Tbx21 primary antibodies
  • Description
    Mouse monoclonal [39D, 3-9D] to T-bet / Tbx21
  • Tested applicationsSuitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant protein purified from E.coli

  • Positive control
    • Th1-polarized mouse CD4+ T cells

Properties

Applications

Our Abpromise guarantee covers the use of ab91103 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 2 µg/ml. Predicted molecular weight: 58 kDa.
IP Use at an assay dependent dilution.

Target

  • FunctionTranscription factor that controls the expression of the TH1 cytokine, interferon-gamma. Initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs.
  • Tissue specificityT-cell specific.
  • Involvement in diseaseGenetic variations in TBX21 are associated with susceptibility to asthma with nasal polyps and aspirin intolerance (ANPAI) [MIM:208550]. A condition consisting of asthma, aspirin sensitivity and nasal polyposis. Nasal polyposis is due to chronic inflammation of the paranasal sinus mucosa, leading to protrusion of edematous polyps into the nasal cavities.
  • Sequence similaritiesContains 1 T-box DNA-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • T bet antibody
    • T box 21 antibody
    • T box expressed in T cells antibody
    • T box protein 21 antibody
    • T box transcription factor TBX21 antibody
    • T cell specific T box transcription factor antibody
    • T cell specific T box transcription factor T bet antibody
    • T PET antibody
    • T-box protein 21 antibody
    • T-box transcription factor TBX21 antibody
    • T-cell-specific T-box transcription factor T-bet antibody
    • TBET antibody
    • TBLYM antibody
    • TBX 21 antibody
    • Tbx21 antibody
    • TBX21_HUMAN antibody
    • TPET antibody
    • Transcription factor TBLYM antibody
    see all

Anti-T-bet / Tbx21 antibody [39D, 3-9D] images

  • All lanes : Anti-T-bet / Tbx21 antibody [39D, 3-9D] (ab91103) at 2 µg/ml

    Lane 1 : Lysates from control cells
    Lane 2 : Lysates from PMA and Ionomycin-re-activated cells

    Secondary
    HRP anti-mouse IgG

    Predicted band size : 58 kDa

References for Anti-T-bet / Tbx21 antibody [39D, 3-9D] (ab91103)

ab91103 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"