Overview

  • Product name
    T0070907
  • Description
    Potent, selective PPARγ antagonist
  • Biological description
    Potent, selective PPARγ antagonist (IC50 = 1 nM). Antidiabetic actions in vivo. Inhibits rosiglitazone (ab120762). Blocks the recruitment of transcriptional cofactors to the PPARγ/RXR heterodimer.
  • Purity
    > 98%

Properties

References

This product has been referenced in:
  • Schaefer KL  et al. Peroxisome proliferator-activated receptor gamma inhibition prevents adhesion to the extracellular matrix and induces anoikis in hepatocellular carcinoma cells. Cancer Res 65:2251-9 (2005). Read more (PubMed: 15781638) »
  • Rockwell CE & Kaminski NE A cyclooxygenase metabolite of anandamide causes inhibition of interleukin-2 secretion in murine splenocytes. J Pharmacol Exp Ther 311:683-90 (2004). Read more (PubMed: 15284281) »
  • Lee G  et al. T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities. J Biol Chem 277:19649-57 (2002). Read more (PubMed: 11877444) »

See 0 Publications for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab120876.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

Sign up