Overview

  • Product name
  • Description
    Rabbit polyclonal to TAB1
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    This antibody was raised against a synthetic peptide corresponding to 13 amino acids in the center of TAB1 (Human).

  • Positive control
    • 3T3 cell lysate for Western blot.
  • General notes


    This antibody can be used for the detection of TAB1 by Western blot at 0.5 to 1 µg/ml.

Properties

Applications

Our Abpromise guarantee covers the use of ab25878 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 55 kDa).
ICC/IF Use a concentration of 1 µg/ml.

Target

  • Function
    May be an important signaling intermediate between TGFB receptors and MAP3K7/TAK1. May play an important role in mammalian embryogenesis.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Contains 1 PP2C-like domain.
  • Post-translational
    modifications
    Monoubiquitinated. Deubiquitinated by Y.enterocolitica YopP.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2310012M03Rik antibody
    • 3'-Tab1 antibody
    • MAP3K7IP 1 antibody
    • MAP3K7IP1 antibody
    • MGC57664 antibody
    • Mitogen activated protein kinase kinase kinase 7 interacting protein 1 antibody
    • Mitogen-activated protein kinase kinase kinase 7-interacting protein 1 antibody
    • TAB 1 antibody
    • TAB1 antibody
    • TAB1_HUMAN antibody
    • TAK1 binding protein 1 antibody
    • TAK1-binding protein 1 antibody
    • TGF beta activated kinase 1 binding protein 1 antibody
    • TGF-beta activated kinase 1/MAP3K7 binding protein 1 antibody
    • TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 antibody
    • TGF-beta-activated kinase 1-binding protein 1 antibody
    • Transforming growth factor beta activated kinase binding protein 1 antibody
    see all

Images

  • Lane 1 : Anti-TAB1 antibody (ab25878) at 0.5 µg/ml
    Lane 2 : Anti-TAB1 antibody (ab25878) at 1 µg/ml
    Lane 3 : Anti-TAB1 antibody (ab25878) at 2 µg/ml

    Lane 1 : 3T3 cell lysate 15ug
    Lane 2 : 3T3 cell lysate 15ug
    Lane 3 : 3T3 cell lysate 15ug


    Predicted band size : 55 kDa
  • ab25878 at 1µg/ml staining TAB1 in K562 cells By ICC/IF

References

This product has been referenced in:
  • Jin HS  et al. cIAP1, cIAP2, and XIAP act cooperatively via nonredundant pathways to regulate genotoxic stress-induced nuclear factor-kappaB activation. Cancer Res 69:1782-91 (2009). WB ; Human . Read more (PubMed: 19223549) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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