Overview

  • Product nameAnti-TAB3 antibody
    See all TAB3 primary antibodies
  • Description
    Rabbit polyclonal to TAB3
  • Specificityab79289 detects endogenous levels of total TAB3 protein.
  • Tested applicationsSuitable for: WB, IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic non-phosphopeptide derived from human TAB3 around the phosphorylation site of serine 439 (R-R-SP-I-Q).

  • Positive control
    • HepG2 and K562 cell extracts; human brain tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab79289 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 79 kDa (predicted molecular weight: 79 kDa).
IHC-P 1/50 - 1/100.
ELISA 1/20000.

Target

  • FunctionAdapter linking MAP3K7/TAK1 and TRAF6 or TRAF2. Mediator of MAP3K7 activation, respectively in the IL1 and TNF signaling pathways. Plays a role in activation of NF-kappa-B and AP1 transcription factor. Isoform 2 may be an oncogenic factor.
  • Tissue specificityWidely expressed. Constitutively overexpressed in certain tumor tissues. Isoform 1 is a major transcript while isoform 2 is a minor transcript.
  • Sequence similaritiesContains 1 CUE domain.
    Contains 1 RanBP2-type zinc finger.
  • Post-translational
    modifications
    Ubiquitinated; following IL1 stimulation or TRAF6 overexpression.
  • Information by UniProt
  • Database links
  • Alternative names
    • MAP3K7IP 3 antibody
    • Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 antibody
    • NAP1 antibody
    • NF-kappa-B-activating protein 1 antibody
    • NFkB activating protein 1 antibody
    • TAB-3 antibody
    • Tab3 antibody
    • TAB3_HUMAN antibody
    • TAK1 binding protein 3 antibody
    • TAK1-binding protein 3 antibody
    • TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 antibody
    • TGF-beta-activated kinase 1-binding protein 3 antibody
    see all

Anti-TAB3 antibody images

  • ab79289 at 1/50 dilution staining TAB3 in human brain by Immunohistochemistry, Paraffin-embedded tissue, in the absence or presence of the immunising peptide.
  • All lanes : Anti-TAB3 antibody (ab79289) at 1/500 dilution

    Lane 1 : HepG2 cell extract
    Lane 2 : K562 cell extract
    Lane 3 : K562 cell extract with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 79 kDa
    Observed band size : 79 kDa

References for Anti-TAB3 antibody (ab79289)

ab79289 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"