Overview

  • Product nameAnti-TACC3 antibody
    See all TACC3 primary antibodies
  • Description
    Mouse monoclonal to TACC3
  • Tested applicationsSuitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: MSLQVLNDKN VSNEKNTENC DFLFSPPEVT GRSSVLRVSQ KENVPPKNLA KAMKVTFQTP LRDPQTHRIL SPSMASKLEA PFTQDDTLGL ENSHPVWTQK , corresponding to amino acids 1-101 of Human TACC3

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • IsotypeIgG3
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab56595 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration. PubMed: 22472443
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 90 kDa.
IHC-P Use a concentration of 3 µg/ml.

Target

  • FunctionPlays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). May be involved in the control of cell growth and differentiation. May contribute to cancer.
  • Sequence similaritiesBelongs to the TACC family.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • ERIC 1 antibody
    • ERIC-1 antibody
    • ERIC1 antibody
    • MGC117382 antibody
    • MGC133242 antibody
    • OTTHUMP00000113796 antibody
    • TACC3 antibody
    • TACC3_HUMAN antibody
    • Transforming acidic coiled coil containing protein 3 antibody
    • Transforming acidic coiled-coil-containing protein 3 antibody
    see all

Anti-TACC3 antibody images

  • TACC3 antibody (ab56595) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human tonsil.


  • Predicted band size : 90 kDa
    TACC3 antibody (ab56595) at 1ug/lane + HeLa cell lysate at 25ug/lane.

References for Anti-TACC3 antibody (ab56595)

This product has been referenced in:
  • Gutiérrez-Caballero C  et al. TACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation. Biol Open N/A:N/A (2015). ICC/IF, WB ; Human . Read more (PubMed: 25596274) »
  • Carvalhal S  et al. The nucleoporin ALADIN regulates Aurora A localization to ensure robust mitotic spindle formation. Mol Biol Cell 26:3424-38 (2015). Read more (PubMed: 26246606) »

See all 6 Publications for this product

Product Wall

Thank you for your inquiry, which was passed along to me from my colleague Chris in Marketing.

I BLASTed the immunogen sequence for ab56595 against mouse and the homology was only 66%. Generally we say that anything with >85% sequence homo...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"