Overview

  • Product nameAnti-TAF15 antibody
    See all TAF15 primary antibodies
  • Description
    Rabbit polyclonal to TAF15
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to a region within amino acids 200-250 of Human TAF15 (Swiss-Prot Q92804).

  • Positive control
    • Human stomach adenocarcinoma

Properties

Applications

Our Abpromise guarantee covers the use of ab84369 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/100 - 1/500.
    Antigen exposure is recommended.
    Antigen exposure with citrate buffer will enhance staining.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionRNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Can enter the preinitiation complex together with the RNA polymerase II (Pol II).
    • Tissue specificityUbiquitous. Observed in all fetal and adult tissues.
    • Involvement in diseaseNote=A chromosomal aberration involving TAF15/TAF2N is found in a form of extraskeletal myxoid chondrosarcomas (EMC). Translocation t(9;17)(q22;q11) with NR4A3.
    • Sequence similaritiesBelongs to the RRM TET family.
      Contains 1 RanBP2-type zinc finger.
      Contains 1 RRM (RNA recognition motif) domain.
    • Post-translational
      modifications
      Dimethylated by PRMT1 at Arg-206 to asymmetric dimethylarginine. The methylation may favor nuclear localization and positive regulation of TAF15 transcriptional activity.
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localizationNucleus. Cytoplasm. Shuttles from the nucleus to the cytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • 68 kDa TATA-binding protein-associated factor antibody
      • Npl3 antibody
      • RBP56 antibody
      • RBP56_HUMAN antibody
      • RNA binding protein 56 antibody
      • RNA-binding protein 56 antibody
      • TAF antibody
      • TAF(II)68 antibody
      • TAF15 antibody
      • TAF15 RNA polymerase II TATA box binding protein (TBP) associated factor 68kDa antibody
      • TAF2N antibody
      • TAFII68 antibody
      • TATA-binding protein-associated factor 2N antibody
      see all

    Anti-TAF15 antibody images

    • ab84369 at 1/250, staining human TAF15 in a section of human stomach adenocarcinoma by immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Detection: DAB staining using anti-rabbit antibody at 1/100.

    References for Anti-TAF15 antibody (ab84369)

    ab84369 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab84369.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"