Overview

  • Product nameAnti-TAF1C antibody
    See all TAF1C primary antibodies
  • Description
    Rabbit polyclonal to TAF1C
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Guinea pig
  • Immunogen

    Synthetic peptide corresponding to a region within C-terminal amino acids 701-750 (RRHRGETSET QTQSKRPKRR TQLSSTFSSF TSYLDSPDAS SAPRSQDLST) of Mouse TAF1C (NP_067416).

  • Positive control
    • Mouse Uterus Lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab108281 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 95 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionComponent of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • RNA polymerase I-specific TBP-associated factor 110 kDa antibody
    • SL1 antibody
    • Taf1c antibody
    • TAF1C_HUMAN antibody
    • TAFI110 antibody
    • TAFI95 antibody
    • TATA box binding protein associated factor 1C antibody
    • TATA box-binding protein-associated factor 1C antibody
    • TATA box-binding protein-associated factor RNA polymerase I subunit C antibody
    • TBP associated factor 1C antibody
    • TBP associated factor RNA polymerase I 95 kDa antibody
    • TBP associated factor, RNA polymerase I, 110-KD antibody
    • TBP-associated factor 1C antibody
    • Transcription initiation factor SL1/TIF-IB subunit C antibody
    see all

Anti-TAF1C antibody images

  • Anti-TAF1C antibody (ab108281) at 1 µg/ml + Mouse Uterus Lysate at 10 µg

    Predicted band size : 95 kDa

References for Anti-TAF1C antibody (ab108281)

ab108281 has not yet been referenced specifically in any publications.

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