Overview

  • Product name
    Anti-Tafazzin / TAZ antibody
    See all Tafazzin / TAZ primary antibodies
  • Description
    Rabbit polyclonal to Tafazzin / TAZ
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Chimpanzee, Baboon, Macaque monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 100 - 200 of Human Tafazzin/ TAZ.

  • Positive control
    • This antibody gave a positive signal in both Human and Mouse Heart tissue lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituent: PBS
    Note: Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab105104 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa).

Target

  • Function
    Some isoforms may be involved in cardiolipin (CL) metabolism.
  • Tissue specificity
    High levels in cardiac and skeletal muscle. Up to 10 isoforms can be present in different amounts in different tissues. Most isoforms are ubiquitous. Isoforms that lack the N-terminus are found in leukocytes and fibroblasts, but not in heart and skeletal muscle. Some forms appear restricted to cardiac and skeletal muscle or to leukocytes.
  • Involvement in disease
    Barth syndrome
  • Sequence similarities
    Belongs to the taffazin family.
  • Domain
    The hydrophilic domain may serve as an exposed loop interacting with other proteins.
  • Cellular localization
    Cytoplasm and Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Barth syndrome antibody
    • BTHS antibody
    • Cardiomyopathy dilated 3A (X linked) antibody
    • CMD3A antibody
    • EFE antibody
    • EFE2 antibody
    • Endocardial fibroelastosis 2 antibody
    • G4.5 antibody
    • LVNCX antibody
    • Protein G4.5 antibody
    • Tafazzin antibody
    • TAZ antibody
    • TAZ protein antibody
    • TAZ_HUMAN antibody
    • Taz1 antibody
    see all

Images

  • All lanes : Anti-Tafazzin / TAZ antibody (ab105104) at 1 µg/ml

    Lane 1 : Human heart tissue lysate - total protein (ab29431)
    Lane 2 : Heart (Mouse) Tissue Lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 33 kDa
    Observed band size : 33 kDa
    Additional bands at : 110 kDa,65 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 1 minute

References

This product has been referenced in:
  • Eirin A  et al. Restoration of Mitochondrial Cardiolipin Attenuates Cardiac Damage in Swine Renovascular Hypertension. J Am Heart Assoc 5:N/A (2016). Read more (PubMed: 27247333) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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