Overview

  • Product name
    Anti-Tafazzin / TAZ antibody
    See all Tafazzin / TAZ primary antibodies
  • Description
    Goat polyclonal to Tafazzin / TAZ
  • Specificity
    This antibody is expected to recognise isoforms 1 to 4. (NP_000107.1; NP_851828.1; NP_851829.1; NP_851830.1, respectively).
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Dog, Chimpanzee
  • Immunogen

    Synthetic peptide:

    C-HLKTQAEQLHNH

    (Human) from the C Terminus of the protein sequence (according to NP_000107.1; NP_851828.1; NP_851829.1; NP_851830.1.).

  • Positive control
    • Human heart lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab40004 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notes
    ELISA: 1/32000 - antibody limit dilution.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 33 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Some isoforms may be involved in cardiolipin (CL) metabolism.
    • Tissue specificity
      High levels in cardiac and skeletal muscle. Up to 10 isoforms can be present in different amounts in different tissues. Most isoforms are ubiquitous. Isoforms that lack the N-terminus are found in leukocytes and fibroblasts, but not in heart and skeletal muscle. Some forms appear restricted to cardiac and skeletal muscle or to leukocytes.
    • Involvement in disease
      Barth syndrome
    • Sequence similarities
      Belongs to the taffazin family.
    • Domain
      The hydrophilic domain may serve as an exposed loop interacting with other proteins.
    • Cellular localization
      Cytoplasm and Membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Barth syndrome antibody
      • Cardiomyopathy dilated 3A (X linked) antibody
      • EFE2 antibody
      • Endocardial fibroelastosis 2 antibody
      • Protein G4.5 antibody
      • Tafazzin antibody
      • TAZ antibody
      • TAZ protein antibody
      • TAZ_HUMAN antibody
      see all

    Anti-Tafazzin / TAZ antibody images

    References for Anti-Tafazzin / TAZ antibody (ab40004)

    This product has been referenced in:
    • Gonzalvez F  et al. Cardiolipin provides an essential activating platform for caspase-8 on mitochondria. J Cell Biol 183:681-96 (2008). WB ; Human . Read more (PubMed: 19001123) »

    See 1 Publication for this product

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