Overview

  • Product nameAnti-Talin 2 antibody [68E7]
    See all Talin 2 primary antibodies
  • Description
    Mouse monoclonal [68E7] to Talin 2
  • Tested applicationsSuitable for: IHC-Fr, ICC/IF, IP, WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Recombinant fragment, corresponding to amino acids 489-911 of Mouse Talin 2.

  • Positive control
    • Fibroblasts
  • General notesGrowth Conditions: RPMI1650 + Glu + Pen + Strep + 10% FCS @ 37°C + 5%CO2

Properties

Applications

Our Abpromise guarantee covers the use of ab105458 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr Use at an assay dependent concentration.
ICC/IF 1/100 - 1/1000.
IP 1/100 - 1/1000.
WB 1/100 - 1/1000. Predicted molecular weight: 272 kDa.
ELISA 1/100 - 1/1000.

Target

  • FunctionAs a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity.
  • Sequence similaritiesContains 1 FERM domain.
    Contains 1 I/LWEQ domain.
  • Cellular localizationCell junction > focal adhesion. Cell junction > synapse. Cell membrane. Cytoplasm > cytoskeleton. Focal adhesion plaques and synapses.
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp451B1011 antibody
    • DKFZp686I0976 antibody
    • DKFZp686K0979 antibody
    • ILWEQ antibody
    • KIAA0320 antibody
    • Talin-2 antibody
    • talin2 antibody
    • TLN 2 antibody
    • TLN2 antibody
    • TLN2_HUMAN antibody
    see all

References for Anti-Talin 2 antibody [68E7] (ab105458)

This product has been referenced in:
  • Debrand E  et al. Talin 2 is a large and complex gene encoding multiple transcripts and protein isoforms. FEBS J 276:1610-28 (2009). Read more (PubMed: 19220457) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab105458.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"