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Amino Acid Sequence
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- CTCL tumor antigen HD CL 09
- CTCL-associated antigen HD-CL-09
- Cutaneous T cell lymphoma tumor antigen HD CL 09
Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK.
Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Contains 1 protein kinase domain.
Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.
Cytoplasm. Cell membrane. Also localized to the peripheral cell membrane.
Information by UniProt
has not yet been referenced specifically in any publications.
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