Specificityab124841 recognizes Human TAOK1 when phosphorylated at Serine 181, TAOK2 when phosphorylated at Serine 181 and TAOK3 when phosphorylated at Serine 177.
Tested applicationsSuitable for:
WB, IHC-Pmore details Unsuitable for:
ICC or IP
Mouse, Rat, Human
corresponding to Human TAOK3. Synthetic peptide corresponding to residues surrounding Serine 181 of Human TAO kinase 2 (Q9UL54) or Serine 181 of TAO kinase 1 (Q7L7X30) or Serine 177 of TAO kinase 3 (Q9H2K8).
293T cell lysates and Human colonic adenocarcinoma tissue.
This product is a recombinant rabbit monoclonal antibody.
Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.
Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Cellular localizationTAOK3: Cytoplasm. Cell membrane. Also localized to the peripheral cell membrane.
TAOK2: Cytoplasmic vesicle membrane. Cytoplasm > cytoskeleton. Nucleus. Catalytically active full-length phosphorylated isoform 1 localizes to microtubules in the cytoplasm predominantly on microtubule cables positioned around the nucleus. A C-terminally truncated form of isoform 1 is present in the nucleus; isoform 2 and kinase-defective, as well as full-length isoform 1 are excluded from the nucleus and Cell projection > dendrite. In dendrites, colocalizes with PCDH8.