Overview

  • Product name
  • Description
    Rabbit polyclonal to Tapasin
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Sheep, Horse, Pig, African green monkey
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 359-408 (SVSLSGHLQP PPVTTEQHGA RYACRIHHPS LPASGRSAEV TLEVAGLSGP) of Human Tapasin (NP_003181).

  • Positive control
    • OVCAR-3 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab104806 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 48 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).
  • Tissue specificity
    Neutrophils, mostly in fully differentiated cells.
  • Sequence similarities
    Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
  • Domain
    The N-terminus is required for efficient association with MHC class I molecule and for a stable interaction between MHC I and calreticulin. Binding to TAP is mediated by the C-terminus region.
  • Cellular localization
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • NGS 17 antibody
    • NGS-17 antibody
    • NGS17 antibody
    • TAP associated protein antibody
    • TAP binding protein antibody
    • TAP binding protein (tapasin) antibody
    • TAP BP antibody
    • TAP-associated protein antibody
    • TAP-binding protein antibody
    • TAPA antibody
    • Tapasin antibody
    • TAPBP antibody
    • TPN antibody
    • TPSN antibody
    • TPSN_HUMAN antibody
    see all

Images

  • Anti-Tapasin antibody (ab104806) at 1 µg/ml + OVCAR-3 cell lysate at 10 µg

    Predicted band size : 48 kDa

References

ab104806 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab104806.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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