Anti-TARBP1 antibody (ab115896)
Key features and details
- Rabbit polyclonal to TARBP1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-TARBP1 antibody
See all TARBP1 primary antibodies -
Description
Rabbit polyclonal to TARBP1 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
A 17 amino acids synthetic peptide conjugated to KLH, corresponding to a region near the center of Human TARBP1.
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Positive control
- Human prostate and Human adrenal tissue
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab115896 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Probable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. May act by methylating HIV-1 TAR RNA. -
Sequence similarities
Belongs to the RNA methyltransferase TrmH family. - Information by UniProt
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Database links
- Entrez Gene: 6894 Human
- Omim: 605052 Human
- SwissProt: Q13395 Human
- Unigene: 498115 Human
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Alternative names
- FLJ30482 antibody
- Probable methyltransferase TARBP1 antibody
- TAR (HIV) RNA binding protein 1 antibody
see all
Images
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ab115896, at 5 ug/ml, staining TARBP1 in formalin fixed, paraffin embedded Human Prostate by Immunohistochemistry. Developed using biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
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ab115896, at 5 ug/ml, staining TARBP1 in formalin fixed, paraffin embedded Human adrenal by Immunohistochemistry. Developed using biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
Datasheets and documents
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Datasheet download
References (0)
ab115896 has not yet been referenced specifically in any publications.