Anti-TARBP1 antibody (ab115896)

Overview

• Product nameAnti-TARBP1 antibody
  See all TARBP1 primary antibodies
• Description
  Rabbit polyclonal to TARBP1
• Tested applicationsSuitable for: WB, IHC-Pmore details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Mouse
• Immunogen

  A 17 amino acids synthetic peptide conjugated to KLH, corresponding to a region near the center of Human TARBP1.

• Positive control
  • Human prostate and Human adrenal tissue

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
• Storage bufferPreservative: 0.02% Sodium azide
  Constituent: 99% PBS
• Concentration information loading...
• PurityImmunogen affinity purified
• ClonalityPolyclonal
• IsotypeIgG
• Research areas
  • Microbiology
  • Organism
  • Virus
  • RNA Virus
  • ssRNA positive strand virus
  • HIV

  • Epigenetics and Nuclear Signaling
  • Chromatin Binding Proteins
  • DNA / RNA binding

  • Immunology
  • Immune System Diseases
  • Antiviral Signaling
  • HIV-related

Associated products

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

Applications

Target

• FunctionProbable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. May act by methylating HIV-1 TAR RNA.
• Sequence similaritiesBelongs to the RNA methyltransferase TrmH family.

• Target information above from: UniProt accession Q13395 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 6894 Human
  • Omim: 605052 Human
  • SwissProt: Q13395 Human
  • Unigene: 498115 Human
• Alternative names
  • FLJ30482 antibody
  • Probable methyltransferase TARBP1 antibody
  • TAR (HIV) RNA binding protein 1 antibody

  • TAR antibody
  • TAR RNA loop binding protein antibody
  • TAR RNA-binding protein 1 antibody
  • TAR RNA-binding protein of 185 kDa antibody
  • TARB1_HUMAN antibody
  • TARBP1 antibody
  • TRM3 antibody
  • TRP-185 antibody
  • TRP185 antibody

  see all