- Datasheet
- Specific References
- Protocols
Overview
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Product nameAnti-TARBP1 antibody
See all TARBP1 primary antibodies -
DescriptionRabbit polyclonal to TARBP1
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Host speciesRabbit
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Tested applicationsSuitable for: WB, IHC-Pmore details
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Species reactivityReacts with: Human
Predicted to work with: Mouse
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Immunogen
A 17 amino acids synthetic peptide conjugated to KLH, corresponding to a region near the center of Human TARBP1.
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Positive control
- Human prostate and Human adrenal tissue
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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Storage bufferPreservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
PurityImmunogen affinity purified
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
Applications
Our Abpromise guarantee covers the use of ab115896 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use at an assay dependent concentration. Predicted molecular weight: 182 kDa. | |
| IHC-P | Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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FunctionProbable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. May act by methylating HIV-1 TAR RNA.
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Sequence similaritiesBelongs to the RNA methyltransferase TrmH family.
- Information by UniProt
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Database links
- Entrez Gene: 6894 Human
- Omim: 605052 Human
- SwissProt: Q13395 Human
- Unigene: 498115 Human
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Alternative names
- FLJ30482 antibody
- Probable methyltransferase TARBP1 antibody
- TAR (HIV) RNA binding protein 1 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TARBP1 antibody (ab115896)ab115896, at 5 ug/ml, staining TARBP1 in formalin fixed, paraffin embedded Human Prostate by Immunohistochemistry. Developed using biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TARBP1 antibody (ab115896)ab115896, at 5 ug/ml, staining TARBP1 in formalin fixed, paraffin embedded Human adrenal by Immunohistochemistry. Developed using biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
References
ab115896 has not yet been referenced specifically in any publications.
Customer reviews and Q&As
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