Recombinant
RabMAb

Anti-TARBP1 antibody [EPR8727] (ab150412)

Overview

  • Product name
    Anti-TARBP1 antibody [EPR8727]
    See all TARBP1 primary antibodies
  • Description
    Rabbit monoclonal [EPR8727] to TARBP1
  • Tested applications
    Suitable for: WB, ICC/IFmore details
    Unsuitable for: Flow Cyt,IHC-P or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive)

  • Positive control
    • Jurkat, HeLa, HepG2, 293T and Caco 2 cell lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab150412 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 182 kDa.
ICC/IF 1/100 - 1/250.
  • Application notes
    Is unsuitable for Flow Cyt,IHC-P or IP.
  • Target

    • Function
      Probable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. May act by methylating HIV-1 TAR RNA.
    • Sequence similarities
      Belongs to the RNA methyltransferase TrmH family.
    • Information by UniProt
    • Database links
    • Alternative names
      • FLJ30482 antibody
      • Probable methyltransferase TARBP1 antibody
      • TAR (HIV) RNA binding protein 1 antibody
      • TAR antibody
      • TAR RNA loop binding protein antibody
      • TAR RNA-binding protein 1 antibody
      • TAR RNA-binding protein of 185 kDa antibody
      • TARB1_HUMAN antibody
      • TARBP1 antibody
      • TRM3 antibody
      • TRP-185 antibody
      • TRP185 antibody
      see all

    Images

    • All lanes : Anti-TARBP1 antibody [EPR8727] (ab150412) at 1/1000 dilution

      Lane 1 : Jurkat cell lysate
      Lane 2 : HeLa cell lysate
      Lane 3 : HepG2 cell lysate
      Lane 4 : 293T cell lysate
      Lane 5 : Caco 2 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 182 kDa

    References

    ab150412 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab150412.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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