FunctionReceptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.
Tissue specificityExpressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
Sequence similaritiesBelongs to the G-protein coupled receptor T2R family.