The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Detects a band of approximately 39 kDa (predicted molecular weight: 39 kDa).
FunctionTubulin-folding protein; involved in the final step of the tubulin folding pathway.
Tissue specificityExpressed in the retina. Expressed in the rod and cone photoreceptors, extending from the inner segments (IS), through the outer nuclear layer (ONL) and into the synapses in the outer plexiform layer (OPL). Strongly expressed to the photoreceptor connecting cilium at the tips of the IS (at protein level).
Sequence similaritiesBelongs to the TBCC family. Contains 1 C-CAP/cofactor C-like domain.
Cellular localizationCytoplasm. Detected predominantly in the photoreceptor connecting cilium.