Anti-TBR2 / Eomes antibody - ChIP Grade (ab23345)

Publishing research using ab23345? Please let us know so that we can cite the reference in this datasheet.

ab23345 has been referenced in 100 publications.

  • Leone DP  et al. Compensatory Actions of Ldb Adaptor Proteins During Corticospinal Motor Neuron Differentiation. Cereb Cortex N/A:N/A (2016). PubMed: 26830346
  • Nagao M  et al. Zbtb20 promotes astrocytogenesis during neocortical development. Nat Commun 7:11102 (2016). Mouse . PubMed: 27000654
  • Shashkova EV  et al. Osteoclast-Primed Foxp3+ CD8 T Cells Induce T-bet, Eomesodermin, and IFN-? To Regulate Bone Resorption. J Immunol 197:726-35 (2016). PubMed: 27324129
  • Sessa A  et al. The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways. Cereb Cortex N/A:N/A (2016). PubMed: 27600842
  • Houlihan SL  et al. Upregulation of neurovascular communication through filamin abrogation promotes ectopic periventricular neurogenesis. Elife 5:N/A (2016). Mouse . PubMed: 27664421
  • Shin J  et al. Single-Cell RNA-Seq with Waterfall Reveals Molecular Cascades underlying Adult Neurogenesis. Cell Stem Cell 17:360-72 (2015). Mouse . PubMed: 26299571
  • Zhao PP  et al. Novel function of PIWIL1 in neuronal polarization and migration via regulation of microtubule-associated proteins. Mol Brain 8:39 (2015). PubMed: 26104391
  • de Juan Romero C  et al. Discrete domains of gene expression in germinal layers distinguish the development of gyrencephaly. EMBO J 34:1859-74 (2015). PubMed: 25916825
  • Liu R  et al. Fstl1 is involved in the regulation of radial glial scaffold development. Mol Brain 8:53 (2015). IF . PubMed: 26382033
  • Wong FK  et al. Sustained Pax6 Expression Generates Primate-like Basal Radial Glia in Developing Mouse Neocortex. PLoS Biol 13:e1002217 (2015). IF . PubMed: 26252244
  • Sun GJ  et al. Tangential migration of neuronal precursors of glutamatergic neurons in the adult mammalian brain. Proc Natl Acad Sci U S A 112:9484-9 (2015). IHC (PFA fixed) ; Mouse . PubMed: 26170290
  • Chen Q  et al. EphA4 Regulates the Balance between Self-Renewal and Differentiation of Radial Glial Cells and Intermediate Neuronal Precursors in Cooperation with FGF Signaling. PLoS One 10:e0126942 (2015). IHC-P ; Mouse . PubMed: 25978062
  • Knock E  et al. The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex. Neural Dev 10:13 (2015). IHC . PubMed: 25934499
  • You L  et al. Deficiency of the chromatin regulator BRPF1 causes abnormal brain development. J Biol Chem 290:7114-29 (2015). PubMed: 25568313
  • García-Moreno F & Molnár Z Subset of early radial glial progenitors that contribute to the development of callosal neurons is absent from avian brain. Proc Natl Acad Sci U S A 112:E5058-67 (2015). IHC (PFA fixed) ; Mouse . PubMed: 26305942
  • Brai E  et al. Notch1 activity in the olfactory bulb is odour-dependent and contributes to olfactory behaviour. Eur J Neurosci N/A:N/A (2014). PubMed: 25234246
  • Ye T  et al. Cdk5-mediated phosphorylation of RapGEF2 controls neuronal migration in the developing cerebral cortex. Nat Commun 5:4826 (2014). Mouse . PubMed: 25189171
  • Jacobshagen M  et al. The serotonin 6 receptor controls neuronal migration during corticogenesis via a ligand-independent Cdk5-dependent mechanism. Development 141:3370-7 (2014). IHC (PFA fixed) ; Mouse . PubMed: 25078650
  • Parthasarathy S  et al. Ntf3 acts downstream of Sip1 in cortical postmitotic neurons to control progenitor cell fate through feedback signaling. Development 141:3324-30 (2014). Mouse . PubMed: 25085976
  • Hao H  et al. Identification of a transient Sox5 expressing progenitor population in the neonatal ventral forebrain by a novel cis-regulatory element. Dev Biol 393:183-93 (2014). IHC-FoFr ; Mouse . PubMed: 24954155
  • Mao CA  et al. T-box transcription regulator Tbr2 is essential for the formation and maintenance of Opn4/melanopsin-expressing intrinsically photosensitive retinal ganglion cells. J Neurosci 34:13083-95 (2014). Mouse . PubMed: 25253855
  • Orosco LA  et al. Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology. Nat Commun 5:4692 (2014). PubMed: 25198012
  • Gärtner A  et al. Distinct temporal hierarchies in membrane and cytoskeleton dynamics precede the morphological polarization of developing neurons. J Cell Sci 127:4409-19 (2014). ICC . PubMed: 25128563
  • Wicklow E  et al. HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst. PLoS Genet 10:e1004618 (2014). IHC ; Mouse . PubMed: 25340657
  • Bedzhov I  et al. In vitro culture of mouse blastocysts beyond the implantation stages. Nat Protoc 9:2732-9 (2014). PubMed: 25356584
  • La Fata G  et al. FMRP regulates multipolar to bipolar transition affecting neuronal migration and cortical circuitry. Nat Neurosci 17:1693-700 (2014). PubMed: 25402856
  • Adam Y  et al. Functional transformations of odor inputs in the mouse olfactory bulb. Front Neural Circuits 8:129 (2014). PubMed: 25408637
  • Cambuli F  et al. Epigenetic memory of the first cell fate decision prevents complete ES cell reprogramming into trophoblast. Nat Commun 5:5538 (2014). IF . PubMed: 25423963
  • Arnò B  et al. Neural progenitor cells orchestrate microglia migration and positioning into the developing cortex. Nat Commun 5:5611 (2014). PubMed: 25425146
  • Mirzaa GM  et al. De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome. Nat Genet 46:510-5 (2014). IHC ; Mouse . PubMed: 24705253
  • Zhu D  et al. Lysine-specific demethylase 1 regulates differentiation onset and migration of trophoblast stem cells. Nat Commun 5:3174 (2014). ICC/IF ; Mouse . PubMed: 24448552
  • Gertz CC  et al. Diverse behaviors of outer radial glia in developing ferret and human cortex. J Neurosci 34:2559-70 (2014). PubMed: 24523546
  • Naveau E  et al. Alteration of rat fetal cerebral cortex development after prenatal exposure to polychlorinated biphenyls. PLoS One 9:e91903 (2014). IHC (PFA fixed) . PubMed: 24642964
  • Soares FA  et al. Investigating the feasibility of scale up and automation of human induced pluripotent stem cells cultured in aggregates in feeder free conditions. J Biotechnol 173:53-8 (2014). IHC (PFA fixed) ; Human . PubMed: 24440272
  • Choi J  et al. Activated retinoid receptors are required for the migration and fate maintenance of subsets of cortical neurons. Development 141:1151-60 (2014). PubMed: 24504337
  • Sweeney NT  et al. Tbr2 is required to generate a neural circuit mediating the pupillary light reflex. J Neurosci 34:5447-53 (2014). PubMed: 24741035
  • Kielar M  et al. Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human. Nat Neurosci 17:923-33 (2014). Mouse, Human . PubMed: 24859200
  • Ono K  et al. Development of the prethalamus is crucial for thalamocortical projection formation and is regulated by Olig2. Development 141:2075-84 (2014). PubMed: 24803655
  • Zuccotti A  et al. The transcription factor Fezf2 directs the differentiation of neural stem cells in the subventricular zone toward a cortical phenotype. Proc Natl Acad Sci U S A 111:10726-31 (2014). PubMed: 25002477
  • Zander MA  et al. The Snail transcription factor regulates the numbers of neural precursor cells and newborn neurons throughout mammalian life. PLoS One 9:e104767 (2014). IHC-Fr ; Mouse . PubMed: 25136812
  • Nowotschin S  et al. The T-box transcription factor Eomesodermin is essential for AVE induction in the mouse embryo. Genes Dev 27:997-1002 (2013). ChIP, IHC - Wholemount ; Mouse . PubMed: 23651855
  • Dudok JJ  et al. MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex. J Neurosci 33:8518-27 (2013). IHC-Fr ; Mouse . PubMed: 23658188
  • Dai Q  et al. BEND6 is a nuclear antagonist of Notch signaling during self-renewal of neural stem cells. Development 140:1892-902 (2013). IHC (PFA fixed) ; Mouse . PubMed: 23571214
  • Tyler WA & Haydar TF Multiplex genetic fate mapping reveals a novel route of neocortical neurogenesis, which is altered in the Ts65Dn mouse model of Down syndrome. J Neurosci 33:5106-19 (2013). IHC-FoFr ; Mouse . PubMed: 23516277
  • Furutachi S  et al. p57 controls adult neural stem cell quiescence and modulates the pace of lifelong neurogenesis. EMBO J 32:970-81 (2013). IHC-FoFr ; Mouse . PubMed: 23481253
  • Cloëtta D  et al. Inactivation of mTORC1 in the developing brain causes microcephaly and affects gliogenesis. J Neurosci 33:7799-810 (2013). ICC/IF ; Mouse . PubMed: 23637172
  • Oshikawa M  et al. Cortical excitatory neurons become protected from cell division during neurogenesis in an Rb family-dependent manner. Development 140:2310-20 (2013). IHC-Fr ; Mouse . PubMed: 23615279
  • Huber M  et al. IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis. J Clin Invest 123:247-60 (2013). WB ; Mouse . PubMed: 23221338
  • Cunningham CL  et al. Diversity of neural precursor cell types in the prenatal macaque cerebral cortex exists largely within the astroglial cell lineage. PLoS One 8:e63848 (2013). IHC-Fr . PubMed: 23724007
  • Rash BG  et al. Cortical gyrification induced by fibroblast growth factor 2 in the mouse brain. J Neurosci 33:10802-14 (2013). PubMed: 23804101
  • Li Q  et al. ADAM17 is critical for multipolar exit and radial migration of neuronal intermediate progenitor cells in mice cerebral cortex. PLoS One 8:e65703 (2013). IHC-Fr ; Mouse . PubMed: 23755270
  • Sultan S  et al. Doxycycline increases neurogenesis and reduces microglia in the adult hippocampus. Front Neurosci 7:131 (2013). IHC ; Mouse . PubMed: 23898238
  • Hasan SM  et al. Mcl1 regulates the terminal mitosis of neural precursor cells in the mammalian brain through p27Kip1. Development 140:3118-27 (2013). PubMed: 23824576
  • Poluch S & Juliano SL Fine-tuning of Neurogenesis Is Essential for the Evolutionary Expansion of the Cerebral Cortex. Cereb Cortex N/A:N/A (2013). PubMed: 23968831
  • Shibasaki T  et al. PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus. Cereb Cortex 23:1824-35 (2013). PubMed: 22705452
  • Leung CY & Zernicka-Goetz M Angiomotin prevents pluripotent lineage differentiation in mouse embryos via Hippo pathway-dependent and -independent mechanisms. Nat Commun 4:2251 (2013). IHC-P . PubMed: 23903990
  • Sultan S  et al. D-serine increases adult hippocampal neurogenesis. Front Neurosci 7:155 (2013). PubMed: 24009551
  • Gebara E  et al. Adult hippocampal neurogenesis inversely correlates with microglia in conditions of voluntary running and aging. Front Neurosci 7:145 (2013). IHC . PubMed: 23970848
  • Zhang K  et al. CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development. Dev Biol 383:15-27 (2013). PubMed: 24036311
  • Okamoto M  et al. TAG-1-assisted progenitor elongation streamlines nuclear migration to optimize subapical crowding. Nat Neurosci 16:1556-66 (2013). PubMed: 24056697
  • Stottmann RW  et al. A mutation in Tubb2b, a human polymicrogyria gene, leads to lethality and abnormal cortical development in the mouse. Hum Mol Genet 22:4053-63 (2013). Mouse . PubMed: 23727838
  • Nowakowski TJ  et al. Loss of functional Dicer in mouse radial glia cell-autonomously prolongs cortical neurogenesis. Dev Biol 382:530-7 (2013). IHC-Fr ; Mouse . PubMed: 24012747
  • Chien Y  et al. Misregulated progesterone secretion and impaired pregnancy in CYP11A1 transgenic mice. Biol Reprod 89:91 (2013). IHC ; Mouse . PubMed: 23966322
  • Dominguez MH  et al. POU-III transcription factors (Brn1, Brn2, and Oct6) influence neurogenesis, molecular identity, and migratory destination of upper-layer cells of the cerebral cortex. Cereb Cortex 23:2632-43 (2013). PubMed: 22892427
  • Saulnier A  et al. The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals. Cereb Cortex 23:2552-67 (2013). PubMed: 22923088
  • Saillour Y  et al. Beta tubulin isoforms are not interchangeable for rescuing impaired radial migration due to Tubb3 knockdown. Hum Mol Genet N/A:N/A (2013). Mouse . PubMed: 24179174
  • Nishino J  et al. A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties. Elife 2:e00924 (2013). ICC/IF ; Mouse . PubMed: 24192035
  • Hu G & Chen J A genome-wide regulatory network identifies key transcription factors for memory CD8? T-cell development. Nat Commun 4:2830 (2013). ChIP . PubMed: 24335726
  • Mi D  et al. Identification of genomic regions regulating Pax6 expression in embryonic forebrain using YAC reporter transgenic mouse lines. PLoS One 8:e80208 (2013). IHC-P ; Mouse . PubMed: 24223221
  • Kelava I  et al. Abundant occurrence of basal radial glia in the subventricular zone of embryonic neocortex of a lissencephalic primate, the common marmoset Callithrix jacchus. Cereb Cortex 22:469-81 (2012). IHC-Fr ; Marmoset (common) . PubMed: 22114084
  • Asanoma K  et al. SATB Homeobox Proteins Regulate Trophoblast Stem Cell Renewal and Differentiation. J Biol Chem 287:2257-68 (2012). WB . PubMed: 22123820
  • Roque T  et al. Lack of a p21waf1/cip -dependent G1/S checkpoint in neural stem and progenitor cells after DNA damage in vivo. Stem Cells 30:537-47 (2012). ICC/IF ; Mouse . PubMed: 22162343
  • Wilsch-Bräuninger M  et al. Basolateral rather than apical primary cilia on neuroepithelial cells committed to delamination. Development 139:95-105 (2012). IHC-Fr ; Mouse . PubMed: 22096071
  • Endo M  et al. Ror family receptor tyrosine kinases regulate the maintenance of neural progenitor cells in the developing neocortex. J Cell Sci 125:2017-29 (2012). Mouse . PubMed: 22328498
  • Shi Y  et al. Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses. Nat Neurosci 15:477-86, S1 (2012). ICC/IF ; Human . PubMed: 22306606
  • Lehtinen MK  et al. The cerebrospinal fluid provides a proliferative niche for neural progenitor cells. Neuron 69:893-905 (2011). Rat . PubMed: 21382550
  • Ip BK  et al. The corticofugal neuron-associated genes ROBO1, SRGAP1, and CTIP2 exhibit an anterior to posterior gradient of expression in early fetal human neocortex development. Cereb Cortex 21:1395-407 (2011). IHC ; Human . PubMed: 21060114
  • Gatz SA  et al. Requirement for DNA ligase IV during embryonic neuronal development. J Neurosci 31:10088-100 (2011). IHC-Fr ; Mouse . PubMed: 21734301
  • Winpenny E  et al. Sequential generation of olfactory bulb glutamatergic neurons by Neurog2-expressing precursor cells. Neural Dev 6:12 (2011). IHC-Fr ; Mouse . PubMed: 21466690
  • Coffinier C  et al. Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency. Proc Natl Acad Sci U S A 107:5076-81 (2010). IHC-Fr ; Mouse . PubMed: 20145110
  • Hansen DV  et al. Neurogenic radial glia in the outer subventricular zone of human neocortex. Nature 464:554-561 (2010). PubMed: 20154730
  • Kidder BL & Palmer S Examination of transcriptional networks reveals an important role for TCFAP2C, SMARCA4, and EOMES in trophoblast stem cell maintenance. Genome Res 20:458-72 (2010). ICC/IF, ChIP/Chip ; Mouse . PubMed: 20176728
  • Silver DL  et al. The exon junction complex component Magoh controls brain size by regulating neural stem cell division. Nat Neurosci 13:551-8 (2010). IHC-FoFr ; Mouse . PubMed: 20364144
  • Fietz SA  et al. OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling. Nat Neurosci 13:690-9 (2010). IHC-P, IHC-Fr ; Human, Ferret . PubMed: 20436478
  • Lizarraga SB  et al. Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors. Development 137:1907-17 (2010). IHC-P ; Mouse . PubMed: 20460369
  • Mutch CA  et al. Beta-catenin signaling negatively regulates intermediate progenitor population numbers in the developing cortex. PLoS One 5: (2010). PubMed: 20811503
  • Cho OH  et al. Notch regulates cytolytic effector function in CD8+ T cells. J Immunol 182:3380-9 (2009). WB ; Mouse . PubMed: 19265115
  • Cruz-Guilloty F  et al. Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs. J Exp Med 206:51-9 (2009). ChIP ; Mouse . PubMed: 19139168
  • Pulvers JN & Huttner WB Brca1 is required for embryonic development of the mouse cerebral cortex to normal size by preventing apoptosis of early neural progenitors. Development 136:1859-68 (2009). IHC-Fr ; Mouse . PubMed: 19403657
  • Weimer JM  et al. MARCKS modulates radial progenitor placement, proliferation and organization in the developing cerebral cortex. Development 136:2965-75 (2009). IHC ; Mouse . PubMed: 19666823
  • Meechan DW  et al. Diminished dosage of 22q11 genes disrupts neurogenesis and cortical development in a mouse model of 22q11 deletion/DiGeorge syndrome. Proc Natl Acad Sci U S A 106:16434-45 (2009). ICC/IF ; Mouse . PubMed: 19805316
  • Nichols J  et al. Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo. Development 136:3215-22 (2009). ICC/IF ; Mouse . PubMed: 19710168
  • Lundell TG  et al. Neurogenin1 expression in cell lineages of the cerebellar cortex in embryonic and postnatal mice. Dev Dyn 238:3310-25 (2009). IHC-FoFr ; Mouse . PubMed: 19924827
  • Hryciw T  et al. The fibroblast growth factor receptor substrate 3 adapter is a developmentally regulated microtubule-associated protein expressed in migrating and differentiated neurons. J Neurochem : (2009). IHC-P ; Mouse . PubMed: 19943849
  • Fukuyama T  et al. Histone acetyltransferase CBP is vital to demarcate conventional and innate CD8+ T-cell development. Mol Cell Biol 29:3894-904 (2009). WB ; Mouse . PubMed: 19433445
  • Estivill-Torrús G  et al. Absence of LPA1 signaling results in defective cortical development. Cereb Cortex 18:938-50 (2008). IHC-P ; Mouse . PubMed: 17656621
  • Konno D  et al. Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis. Nat Cell Biol 10:93-101 (2008). IHC-Fr ; Mouse . PubMed: 18084280
  • Kawaguchi A  et al. Single-cell gene profiling defines differential progenitor subclasses in mammalian neurogenesis. Development 135:3113-24 (2008). IHC-Fr ; Mouse . PubMed: 18725516
  • De Pietri Tonelli D  et al. miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex. Development 135:3911-21 (2008). IHC-Fr ; Mouse . PubMed: 18997113
  • Ng RK  et al. Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5. Nat Cell Biol 10:1280-90 (2008). IHC-P ; Mouse . PubMed: 18836439

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"