Anti-TBRG1 antibody - Aminoterminal end (ab71318)

Overview

  • Product nameAnti-TBRG1 antibody - Aminoterminal end
    See all TBRG1 primary antibodies
  • Description
    Rabbit polyclonal to TBRG1 - Aminoterminal end
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide selected from the N terminal region of human TBRG1 conjugated to KLH

  • Positive control
    • Mouse kidney tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab71318 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/50 - 1/100. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).

Target

  • RelevanceFunction: Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability. Tissue specificity: Widely expressed at low levels in most tissues, with highest levels in pancreas, lung and liver. Expression is decreased in primary tumors including lung, liver, breast, pancreas and kidney carcinomas, chronic lymphocytic leukemia and diffuse large B-cell lymphoma. Similarity: Belongs to the TBRG1 family. Contains 1 FYR C-terminal domain. Contains 1 FYR N-terminal domain. PTM: Ubiquitinated; mediated by MDM2 and leading to its subsequent proteasomal degradation.
  • Cellular localizationNuclear
  • Database links
  • Alternative names
    • NIAM antibody
    • Nuclear interactor of ARF and Mdm2 antibody
    • TB 5 antibody
    • tbrg1 antibody
    • TBRG1 regulator 1 antibody
    • TBRG1_HUMAN antibody
    • Transforming growth factor beta regulator 1 antibody
    see all

Anti-TBRG1 antibody - Aminoterminal end images

  • Anti-TBRG1 antibody - Aminoterminal end (ab71318) at 1/60 dilution + mouse kidney tissue lysates at 35 µg

    Predicted band size : 45 kDa
    Observed band size : 45 kDa

References for Anti-TBRG1 antibody - Aminoterminal end (ab71318)

ab71318 has not yet been referenced specifically in any publications.

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