Overview

  • Product nameAnti-Tbx3 antibody
    See all Tbx3 primary antibodies
  • Description
    Rabbit polyclonal to Tbx3
  • Tested applicationsSuitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 400-450 of Human Tbx3 (NP_057653.3).

  • Positive control
    • HeLa and 293T whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab113275 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Predicted molecular weight: 79 kDa.
IP Use at 2-10 µg/mg of lysate.

Target

  • FunctionTranscriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation.
  • Tissue specificityWidely expressed.
  • Involvement in diseaseDefects in TBX3 are the cause of ulnar-mammary syndrome (UMS) [MIM:181450]. UMS is characterized by ulnar ray defects, obesity, hypogenitalism, delayed puberty, hypoplasia of nipples and apocrine glands.
  • Sequence similaritiesContains 1 T-box DNA-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Bladder cancer related protein XHL antibody
    • T box 3 antibody
    • T-box protein 3 antibody
    • T-box transcription factor TBX3 antibody
    • Tbx3 antibody
    • TBX3 ISO antibody
    • TBX3_HUMAN antibody
    • UMS antibody
    • XHL antibody
    see all

Anti-Tbx3 antibody images

  • All lanes : Anti-Tbx3 antibody (ab113275) at 0.4 µg/ml

    Lane 1 : HeLa whole cell lysate at 50 µg
    Lane 2 : HeLa whole cell lysate at 15 µg
    Lane 3 : HeLa whole cell lysate at 5 µg
    Lane 4 : 293T whole cell lysate at 50 µg


    Predicted band size : 79 kDa


    Exposure time : 3 minutes
  • Detection of Tbx3 by Western Blot of Immunprecipitate.
    ab113275 at 1µg/ml staining Tbx3 in HeLa whole cell lysate immunoprecipitated using ab113275 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
    Detection: Chemiluminescence with exposure time of 3 minutes.

References for Anti-Tbx3 antibody (ab113275)

ab113275 has not yet been referenced specifically in any publications.

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