FunctionTranscriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation.
Tissue specificityWidely expressed.
Involvement in diseaseDefects in TBX3 are the cause of ulnar-mammary syndrome (UMS) [MIM:181450]. UMS is characterized by ulnar ray defects, obesity, hypogenitalism, delayed puberty, hypoplasia of nipples and apocrine glands.
All lanes : Anti-Tbx3 antibody (ab113275) at 0.4 µg/ml
Lane 1 : HeLa whole cell lysate at 50 µg Lane 2 : HeLa whole cell lysate at 15 µg Lane 3 : HeLa whole cell lysate at 5 µg Lane 4 : 293T whole cell lysate at 50 µg
Predicted band size : 79 kDa
Exposure time : 3 minutes
Immunoprecipitation - Tbx3 antibody (ab113275)
Detection of Tbx3 by Western Blot of Immunprecipitate.
ab113275 at 1µg/ml staining Tbx3 in HeLa whole cell lysate immunoprecipitated using ab113275 at 6µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Detection: Chemiluminescence with exposure time of 3 minutes.
References for Anti-Tbx3 antibody (ab113275)
has not yet been referenced specifically in any publications.
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