Overview

  • Product nameAnti-Tbx3 antibody
    See all Tbx3 primary antibodies
  • Description
    Mouse monoclonal to Tbx3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: KENGTSDESS SEQAAFNCFA QASSPAASTV GTSNLKDLCP SEGESDAEAE SKEEHGPEAC DAAKISTTTS EEPCRDKGSP AVKAHLFAAE RPRDSGRLDK , corresponding to amino acids 311-411 of Human Tbx3

Properties

Applications

Our Abpromise guarantee covers the use of ab58264 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 79 kDa.

Target

  • FunctionTranscriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation.
  • Tissue specificityWidely expressed.
  • Involvement in diseaseDefects in TBX3 are the cause of ulnar-mammary syndrome (UMS) [MIM:181450]. UMS is characterized by ulnar ray defects, obesity, hypogenitalism, delayed puberty, hypoplasia of nipples and apocrine glands.
  • Sequence similaritiesContains 1 T-box DNA-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Bladder cancer related protein XHL antibody
    • T box 3 antibody
    • T-box protein 3 antibody
    • T-box transcription factor TBX3 antibody
    • Tbx3 antibody
    • TBX3 ISO antibody
    • TBX3_HUMAN antibody
    • UMS antibody
    • XHL antibody
    see all

Anti-Tbx3 antibody images



  • Predicted band size : 79 kDa
    Tbx3 antibody (ab58264) at 1ug/lane + IMR-32 cell lysate at 25ug/lane.
  • Ab58264 (10 ug/ml) staining of TBX3 in HeLa cells by immunofluorescence.

References for Anti-Tbx3 antibody (ab58264)

This product has been referenced in:
  • Krstic M  et al. The transcriptional regulator TBX3 promotes progression from non-invasive to invasive breast cancer. BMC Cancer 16:671 (2016). WB ; Human . Read more (PubMed: 27553211) »
  • Fillmore CM  et al. Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling. Proc Natl Acad Sci U S A : (2010). WB ; Human . Read more (PubMed: 21098263) »

See all 2 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab58264.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"