For the best experience on the Abcam website please upgrade to a modern browser such as
Storage instructions Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
Storage buffer Preservative: 0.09% Sodium azide Constituent: 99% PBS
Concentration information loading...
Purity Immunogen affinity purified
Purification notes ab123665 is purified through a protein A column, followed by peptide affinity purification.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 58 kDa.
1/10 - 1/50.
Function Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation.
Involvement in disease Defects in TBX5 are the cause of Holt-Oram syndrome (HOS) [MIM:142900]. HOS is a developmental disorder affecting the heart and upper limbs. It is characterized by thumb anomaly and atrial septal defects.
Sequence similarities Contains 1 T-box DNA-binding domain.
Cellular localization Nucleus.
Information by UniProt
Holt Oram syndrome antibody
T box 5 antibody
Anti-TBX5 antibody images
References for Anti-TBX5 antibody (ab123665)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"