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Rabbit polyclonal to TBX5
Synthetic peptide conjugated to KLH, corresponding to N terminal amino acids 1-30 of Human TBX5 (NP_542449.1, NP_852259.1).
Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
Preservative: 0.09% Sodium azide
Constituent: 99% PBS
Concentration information loading...
Immunogen affinity purified
ab123665 is purified through a protein A column, followed by peptide affinity purification.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 58 kDa.
1/10 - 1/50.
Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation.
Involvement in disease
Defects in TBX5 are the cause of Holt-Oram syndrome (HOS) [MIM:142900]. HOS is a developmental disorder affecting the heart and upper limbs. It is characterized by thumb anomaly and atrial septal defects.
Contains 1 T-box DNA-binding domain.
Information by UniProt
Holt Oram syndrome antibody
T box 5 antibody
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"