Overview

  • Product nameAnti-TCEB2 antibody
    See all TCEB2 primary antibodies
  • Description
    Rabbit polyclonal to TCEB2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 20-48 of Human TCEB2 (NP_009039.1).

  • Positive control
    • K-562 cell line lysates

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab123402 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 13 kDa.

Target

  • FunctionSIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
    The elongin BC complex seems to be involved as an adapter protein in the proteasomal degradation of target proteins via different E3 ubiquitin ligase complexes, including the von Hippel-Lindau ubiquitination complex CBC(VHL). By binding to BC-box motifs it seems to link target recruitment subunits, like VHL and members of the SOCS box family, to Cullin/RBX1 modules that activate E2 ubiquitination enzymes.
  • PathwayProtein modification; protein ubiquitination.
  • Sequence similaritiesContains 1 ubiquitin-like domain.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • EloB antibody
    • ELOB_HUMAN antibody
    • Elongin 18 kDa subunit antibody
    • Elongin B antibody
    • Elongin-B antibody
    • RNA polymerase II transcription factor SIII p18 subunit antibody
    • RNA polymerase II transcription factor SIII subunit B antibody
    • SIII antibody
    • SIII p18 antibody
    • TCEB 2 antibody
    • Tceb2 antibody
    • Transcription elongation factor B (SIII) polypeptide 2 antibody
    • Transcription elongation factor B polypeptide 2 antibody
    see all

Anti-TCEB2 antibody images

  • Anti-TCEB2 antibody (ab123402) at 1/100 dilution + K-562 cell line lysates at 35 µg

    Predicted band size : 13 kDa

References for Anti-TCEB2 antibody (ab123402)

ab123402 has not yet been referenced specifically in any publications.

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