Overview

  • Product nameAnti-TCF12 antibody
    See all TCF12 primary antibodies
  • Description
    Rabbit polyclonal to TCF12
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Chimpanzee, Lizard, Rhesus monkey, Gorilla, Chinese Hamster, Orangutan, Elephant
  • Immunogen

    Synthetic peptide within Human TCF12 aa 1-50 (N terminal). The exact sequence is proprietary.
    Database link: NP_996919.1

  • Positive control
    • Human Breast Carcinoma, Human Colon Carcinoma

Properties

Applications

Our Abpromise guarantee covers the use of ab91592 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Antigen retrieval is not essential but may optimise staining.

Antigen retrieval with Tris-EDTA pH9.0 buffer will enhance staining.

Target

  • FunctionBinds specifically to oligomers of E-box motifs. May play important roles during development of the nervous system as well as in other organ systems.
  • Tissue specificityExpressed in several tissues and cell types including skeletal muscle, thymus, and a B-cell line.
  • Sequence similaritiesContains 1 basic helix-loop-helix (bHLH) domain.
  • Domainthe 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • bHLHb20 antibody
    • Class B basic helix-loop-helix protein 20 antibody
    • DNA binding protein HTF4 antibody
    • DNA-binding protein HTF4 antibody
    • E box binding protein antibody
    • E-box-binding protein antibody
    • HEB antibody
    • Helix loop helix transcription factor 4 antibody
    • HsT17266 antibody
    • HTF4 antibody
    • HTF4_HUMAN antibody
    • TCF-12 antibody
    • Tcf12 antibody
    • Transcription factor 12 antibody
    • Transcription factor HTF-4 antibody
    • Transcription factor HTF4 antibody
    see all

Anti-TCF12 antibody images

  • ab91592 at 1/250 dilution detecting TCF12 in formalin fixed, paraffin embedded section of human colon carcinoma by immunohistochemistry.
    Detection with DAB.

References for Anti-TCF12 antibody (ab91592)

ab91592 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"