Overview

  • Product nameAnti-TCN2 antibody
    See all TCN2 primary antibodies
  • Description
    Mouse monoclonal to TCN2
  • Tested applicationsSuitable for: WB, Indirect ELISAmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    GST-tagged recombinant full length protein, corresponding to amino acids 1-401 of Human TCN2

Properties

Applications

Our Abpromise guarantee covers the use of ab76638 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
Indirect ELISA
  • Application notesI-ELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 1 - 5 µg/ml. Predicted molecular weight: 47 kDa.
    Note: This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionPrimary vitamin B12-binding and transport protein. Delivers cobalamin to cells.
    • Involvement in diseaseDefects in TCN2 are the cause of transcobalamin II deficiency (TCN2 deficiency) [MIM:275350]. This results in various forms of anemia.
    • Sequence similaritiesBelongs to the eukaryotic cobalamin transport proteins family.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • D22S676 antibody
      • D22S750 antibody
      • II antibody
      • Macrocytic anemia antibody
      • OTTHUMP00000199117 antibody
      • OTTHUMP00000199118 antibody
      • OTTHUMP00000199119 antibody
      • TC antibody
      • TC II antibody
      • TC II deficiency antibody
      • TC-2 antibody
      • TC2 antibody
      • TCII antibody
      • TCN2 antibody
      • TCN2 deficiency antibody
      • TCO2_HUMAN antibody
      • Transcobalamin 2 antibody
      • Transcobalamin 2 deficiency antibody
      • Transcobalamin II antibody
      • Transcobalamin II; macrocytic anemia antibody
      • Transcobalamin-2 antibody
      • Vitamin B12 binding protein 2 antibody
      see all

    Anti-TCN2 antibody images

    • Anti-TCN2 antibody (ab76638) at 5 µg/ml + immunogen (GST-tagged recombinant full length Human TCN2) at 0.2 µg

      Secondary
      Goat Anti-Mouse IgG (H&L) HRP-conjugated at 1/5000 dilution

      Predicted band size : 47 kDa
      Observed band size : 73 kDa (why is the actual band size different from the predicted?)

    References for Anti-TCN2 antibody (ab76638)

    ab76638 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab76638.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"