Anti-TCR alpha + beta + epithelial tumor antibody [R73 + CC52] (ab5178)

Overview

  • Product nameAnti-TCR alpha + beta + epithelial tumor antibody [R73 + CC52]
  • Description
    Mouse monoclonal [R73 + CC52] to TCR alpha + beta + epithelial tumor
  • SpecificityQuadroma clones producing functional bispecific antibodies were selected by testing the ability of the quadroma products to induce T cells to lyse the appropriate tumor cells.
  • Tested applicationsSuitable for: Celluar Activationmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    This bi-specific antibody was generated by fusion of the R73 producing hybridoma with the CC52 producing hybridoma: R73 = Rat T Blasts and erythrocytes. CC52 = Rat colonic adenocarcinoma cells (CC531)

  • General notesConsists of one half of an antibody that is directed against the rat T cell receptor alpha + beta (clone R73) and for the other half of an antibody directed against an antigen present on tumor cells of epithelial origin (clone CC52).

Properties

Applications

Our Abpromise guarantee covers the use of ab5178 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Celluar Activation
  • Application notesCellular activation: Use at an assay dependant dilution.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    References for Anti-TCR alpha + beta + epithelial tumor antibody [R73 + CC52] (ab5178)

    This product has been referenced in:
    • Beun GD  et al. T-cell retargeting using bispecific monoclonal antibodies in a rat colon carcinoma model: III. Activation of resting T cells and tumor neutralization induced by bispecific antibodies. J Immunother 13:223-31 (1993). Read more (PubMed: 8334106) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab5178.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"